Dengue virus: epidemiology, biology, and disease aetiology

SK Roy, S Bhattacharjee - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV).
Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each …

[HTML][HTML] New insights into the immunopathology and control of dengue virus infection

G Screaton, J Mongkolsapaya, S Yacoub… - Nature Reviews …, 2015 - nature.com
Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …

Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus

L Priyamvada, KM Quicke… - Proceedings of the …, 2016 - National Acad Sciences
Zika virus (ZIKV) is an emerging mosquito-borne flavivirus of significant public health
concern. ZIKV shares a high degree of sequence and structural homology compared with …

[HTML][HTML] Structures of the Zika virus envelope protein and its complex with a flavivirus broadly protective antibody

L Dai, J Song, X Lu, YQ Deng, AM Musyoki, H Cheng… - Cell host & …, 2016 - cell.com
Zika virus (ZIKV), a mosquito-borne flavivirus, is a current global public health concern. The
flavivirus envelope (E) glycoprotein is responsible for virus entry and represents a major …

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

W Dejnirattisai, W Wongwiwat, S Supasa, X Zhang… - Nature …, 2015 - nature.com
Dengue is a rapidly emerging, mosquito-borne viral infection, with an estimated 400 million
infections occurring annually. To gain insight into dengue immunity, we characterized 145 …

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

K Stettler, M Beltramello, DA Espinosa, V Graham… - Science, 2016 - science.org
Zika virus (ZIKV), a mosquito-borne flavivirus with homology to Dengue virus (DENV), has
become a public health emergency. By characterizing memory lymphocytes from ZIKV …

[HTML][HTML] Immunoinformatics design of a novel epitope-based vaccine candidate against dengue virus

AO Fadaka, NRS Sibuyi, DR Martin, M Goboza… - Scientific reports, 2021 - nature.com
Dengue poses a global health threat, which will persist without therapeutic intervention.
Immunity induced by exposure to one serotype does not confer long-term protection against …

The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design

FA Rey, K Stiasny, MC Vaney, M Dellarole… - EMBO reports, 2018 - embopress.org
Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …

[HTML][HTML] Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms

AL Rothman - Nature Reviews Immunology, 2011 - nature.com
Dengue is a mosquito-borne viral disease of expanding geographical range and incidence.
The existence of four viral serotypes and the association of prior dengue virus infection with …

Receptors and routes of dengue virus entry into the host cells

C Cruz-Oliveira, JM Freire… - FEMS microbiology …, 2015 - academic.oup.com
Dengue is the most prevalent arthropod-borne viral disease, caused by dengue virus, a
member of the Flaviviridae family. Its worldwide incidence is now a major health problem …