Systemic sclerosis is an autoimmune connective tissue disease, which is characterised by
immune dysregulation and progressive fibrosis that typically affects the skin, with variable …

Some of the most pressing challenges associated with interstitial lung disease (ILD) are how
best to define, diagnose, and treat connective tissue disease-associated ILD (CTD-ILD) …

Bronchoalveolar lavage (BAL) is a commonly used procedure in the evaluation of lung
disease as it allows for sampling of the lower respiratory tract. In many circumstances, BAL …

Endothelial cell damage and platelet activation contribute to sustained vasculopathy, which
is a key clinical characteristic of systemic sclerosis (SSc), also known as scleroderma …

Systemic sclerosis is an autoimmune disease leading to vasculopathy and fibrosis of skin
and internal organs. Despite likely shared pathogenic mechanisms, the patterns of skin and …

Systemic sclerosis (SSc) is a rare chronic autoimmune disease characterized by
vasculopathy, dysregulation of innate and adaptive immune responses, and progressive …

Introduction Interstitial lung disease (ILD) is a frequent manifestation of systemic sclerosis
(SSc), and cytokines can contribute to the disease pathology. The aim of the current study …

Systemic sclerosis (SSc) is an intricate systemic autoimmune disease with pathological
features such as vascular injury, immune dysregulation, and extensive fibrosis of the skin …

Background: Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is one of the
most relevant complications of SSc and the major cause of death. The pathogenesis of SSc …

Systemic sclerosis-associated interstitial lung disease (SSc-ILD) is rare, poorly understood,
with heterogeneous characteristics resulting in difficult diagnosis. We aimed to …