Next-generation TB vaccines: progress, challenges, and prospects

L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …

Is there still hope for the prophylactic hepatitis C vaccine? A review of different approaches

P Rzymski, AT Jibril, L Rahmah… - Journal of Medical …, 2024 - Wiley Online Library
Despite remarkable progress in the treatment of hepatitis C virus (HCV) infection, it remains
a significant global health burden, necessitating the development of an effective prophylactic …

Stereoselective Synthesis of Sialyl Lewisa Antigen and the Effective Anticancer Activity of Its Bacteriophage Qβ Conjugate as an Anticancer Vaccine

Z Rashidijahanabad, S Ramadan… - Angewandte Chemie …, 2023 - Wiley Online Library
Sialyl Lewisa (sLea), also known as cancer antigen 19‐9 (CA19‐9), is a tumor‐associated
carbohydrate antigen. The overexpression of sLea on the surface of a variety of cancer cells …

A nanoparticle vaccine displaying varicella-zoster virus gE antigen induces a superior cellular immune response than a licensed vaccine in mice and non-human …

Y Li, S Tian, Y Ai, Z Hu, C Ma, M Fu, Z Xu, Y Li… - Frontiers in …, 2024 - frontiersin.org
Herpes zoster (HZ), also known as shingles, remains a significant global health issue and
most commonly seen in elderly individuals with an early exposure history to varicella-zoster …

Development of a Tag/Catcher-mediated capsid virus-like particle vaccine presenting the conserved Neisseria gonorrhoeae SliC antigen that blocks human lysozyme

FG Martinez, RA Zielke, CE Fougeroux, L Li… - Infection and …, 2023 - Am Soc Microbiol
Virus-like particles (VLPs) are promising nanotools for the development of subunit vaccines
due to high immunogenicity and safety. Herein, we explored the versatile and effective …

Enhancing Protective Antibodies against Opioids through Antigen Display on Virus-like Particles

F Shafieichaharberoud, S Lang, C Whalen… - Bioconjugate …, 2023 - ACS Publications
Opioid use disorder (OUD) has become a public health crisis, with recent significant
increases in the number of deaths due to overdose. Vaccination can provide an attractive …

The quest for nanoparticle-powered vaccines in cancer immunotherapy

Z Sun, H Zhao, L Ma, Y Shi, M Ji, X Sun, D Ma… - Journal of …, 2024 - Springer
Despite recent advancements in cancer treatment, this disease still poses a serious threat to
public health. Vaccines play an important role in preventing illness by preparing the body's …

Virus-like particles based on the novel goose parvovirus (NGPV) VP2 protein protect ducks against NGPV challenge

Y Shang, Y Ma, S Tang, X Chen, H Feng, L Li, H Wang… - Vaccines, 2023 - mdpi.com
Novel goose parvovirus (NGPV), a genetic variant of goose parvovirus, has been spreading
throughout China since 2015 and mainly infects ducklings with the symptoms of growth …

Current Advances in Viral Nanoparticles for Biomedicine

X Sun, T Tian, Y Lian, Z Cui - ACS nano, 2024 - ACS Publications
Viral nanoparticles (VNPs) have emerged as crucial tools in the field of biomedicine.
Leveraging their biological and physicochemical properties, VNPs exhibit significant …

mRNA and Adenoviral Vector Vaccine Platforms Utilized in COVID-19 Vaccines: Technologies, Ecosystem, and Future Directions

R Okuyama - Vaccines, 2023 - mdpi.com
New technological platforms, such as mRNA and adenoviral vector vaccines, have been
utilized to develop coronavirus disease 2019 (COVID-19) vaccines. These new modalities …