Functional metabolomics innovates therapeutic discovery of traditional Chinese medicine derived functional compounds

T Wang, J Liu, X Luo, L Hu, H Lu - Pharmacology & Therapeutics, 2021 - Elsevier
Abstract Traditional Chinese medicines (TCMs) produce chemically diverse functional
compounds that are importantly chemical resource for facilitating new drug discovery and …

Recent progress in development and application of DNA, protein, peptide, glycan, antibody, and aptamer microarrays

GM Aparna, KKR Tetala - Biomolecules, 2023 - mdpi.com
Microarrays are one of the trailblazing technologies of the last two decades and have
displayed their importance in all the associated fields of biology. They are widely explored to …

Detection of human visceral leishmaniasis parasites in microscopy images from bone marrow parasitological examination

C Gonçalves, A Borges, V Dias, J Marques, B Aguiar… - Applied Sciences, 2023 - mdpi.com
Visceral Leishmaniasis (VL) is a neglected disease that affects between 50,000 and 90,000
new cases annually worldwide. In Brazil, VL causes about 3500 cases/per year. This chronic …

The Geographical Distribution of Human Cutaneous and Visceral Leishmania Species Identified by Molecular Methods in Iran: A Systematic Review With Meta …

H Hajjaran, R Saberi, A Borjian, M Fakhar… - Frontiers in Public …, 2021 - frontiersin.org
Leishmaniasis is one of the most common vector-borne parasitic diseases in Iran.
Leishmania species identification is necessary for epidemiological aspects, precise …

Nanomedicine in leishmaniasis: A promising tool for diagnosis, treatment and prevention of disease-An update overview

JP Assolini, ACM Carloto, BT da Silva Bortoleti… - European Journal of …, 2022 - Elsevier
Leishmaniasis is a neglected tropical disease that has a wide spectrum of clinical
manifestations, ranging from visceral to cutaneous, with millions of new cases and …

Genetically modified live attenuated vaccine: a potential strategy to combat visceral leishmaniasis

SC Pandey, A Kumar, M Samant - Parasite Immunology, 2020 - Wiley Online Library
Visceral leishmaniasis (VL) is caused by a protozoan parasite Leishmania donovani mainly
influencing the population of tropical and subtropical regions across the globe. The arsenal …

Advance methods for the qualitative and quantitative determination of microorganisms

K Ayhan, S Coşansu, E Orhan-Yanıkan… - Microchemical Journal, 2021 - Elsevier
The next generation microbiological analysis is progressed swiftly due to its numerous
advantages such as sensitivity, reproducibility, accuracy, low cost and rapidity. Although …

Status and perspective of asian neglected tropical diseases

B Sripa, L Leonardo, SJ Hong, A Ito, NW Brattig - Acta tropica, 2022 - Elsevier
Neglected Tropical Diseases (NTDs) affect over 1 billion people and cause 170,000 deaths
each year in the poor and vulnerable populations mainly in the tropical countries. WHO …

DDX3 DEAD-box RNA helicase (Hel67) gene disruption impairs infectivity of Leishmania donovani and induces protective immunity against visceral leishmaniasis

SC Pandey, V Pande, M Samant - Scientific reports, 2020 - nature.com
Visceral leishmaniasis (VL) is a vector-borne disease caused by the digenetic protozoan
parasite Leishmania donovani complex. So far there is no effective vaccine available …

Correlated Hybrid DNA Structures Explored by the oxDNA Model

YP Qiao, CL Ren - Langmuir, 2023 - ACS Publications
Thermodynamically, perfect DNA hybridization can be formed between probes and their
corresponding targets due to the favorable energy. However, this is not the case …