Multi-dimensional liquid chromatography (MD-LC) continues to gain in popularity for
applications where conventional one-dimensional liquid chromatography is insufficient to …

Monoclonal antibodies (mAbs) are a fast-growing class of biopharmaceuticals. They are
widely used in the identification and detection of cell makers, serum analytes, and …

N-glycosylation of therapeutic antibodies starts as a co-translational step followed by a set of
post-translational modifications and is considered as one of the critical quality attributes …

Despite progress in hardware and column technology, the complexity and heterogeneity of
many samples still pose a challenge for state-of-the-art 1D liquid chromatography (LC). As …

Antibody–drug conjugates (ADCs) are biopharmaceuticals produced by chemically linking
small molecules (payloads) to antibodies that possess specific affinity for the target cell. The …

The role of mass spectrometry (MS) has become more important in most application
domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation …

Medicinal plants are rich sources of natural oils such as essential and fixed oils used
traditionally for nutritive as well as medicinal purposes. Most of the traditional formulations or …

The multi-attribute method (MAM), a liquid chromatography-mass spectrometry (LC-MS)-
based peptide mapping method, has gained increased interest and applications in the …

In the past two decades, antibody–drug conjugates have gained increasing attention
because they expand the therapeutic index when compared with that of traditional …

Fully automated analysis of multiple structural attributes of monoclonal antibodies (mAbs)
using three-dimensional liquid chromatography-mass spectrometry (3D-LC-MS) is …