The Role of the Nrf2 Pathway in Airway Tissue Damage Due to Viral Respiratory Infections

AJ Kombe Kombe, L Fotoohabadi, R Nanduri… - International journal of …, 2024 - mdpi.com
Respiratory viruses constitute a significant cause of illness and death worldwide.
Respiratory virus-associated injuries include oxidative stress, ferroptosis, inflammation …

[HTML][HTML] Oxidative Stress Induced by Antivirals: Implications for Adverse Outcomes During Pregnancy and in Newborns

B Costa, MJ Gouveia, N Vale - Antioxidants, 2024 - mdpi.com
Oxidative stress plays a critical role in various physiological and pathological processes,
particularly during pregnancy, where it can significantly affect maternal and fetal health. In …

[HTML][HTML] The Role of Inflammation in the Pathogenesis of Viral Respiratory Infections

AJ Kombe Kombe, L Fotoohabadi, Y Gerasimova… - Microorganisms, 2024 - mdpi.com
Viral respiratory infections (VRIs) are a leading cause of morbidity and mortality worldwide,
making them a significant public health concern. During infection, respiratory viruses …

Nrf2-Keap1 in Cardiovascular Disease: Which is the Cart and Which the Horse?

N Dhyani, C Tian, L Gao, TL Rudebush… - Physiology, 2024 - journals.physiology.org
High levels of oxidant stress in the form of reactive oxidant species are prevalent in the
circulation and tissues in various types of cardiovascular disease including heart failure …

Sulforaphane's Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)-Dependent and-Independent Mechanism of Anti-SARS-CoV-2 Activity

Z Yan, W Liang, L Zhu, I Kreso… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
It is well established that Nrf2 plays a crucial role in anti-oxidant and anti-inflammatory
functions. However, its antiviral capabilities remain less explored. Despite this, several Nrf2 …

Do Repeated Respiratory Tract Infections Predispose to Amoebic Meningoencephalitis Caused by Free-Living Amoebae?

V Kandi - Cureus, 2024 - pmc.ncbi.nlm.nih.gov
Recent reports of fatal meningoencephalitis from Kerala, South India, are creating ripples
among medical and health administrations. Free-living amoebae (FLA) have been attributed …

[PDF][PDF] Nrf2-Keap1 in Cardiovascular Disease: Which Is the Cart and Which the Horse?

IH Zucker - vascular - researchgate.net
The evolution of an oxygen (O2)-based atmosphere has made it possible for life to exist on
Earth in multiple and unique forms. Close to 4 billion years ago, solar radiation initiated a …