Drug delivery to the lungs by inhalation offers a targeted drug therapy for respiratory
diseases. However, the therapeutic efficacy of inhaled drugs is limited by their rapid …

This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …

In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …

With the rapidly growing popularity and sophistication of inhalation therapy, there is an
increasing demand for tailor-made inhalable drug particles capable of affording the most …

Particulate drug delivery systems have become important in experimental pharmaceutics
and clinical medicine. The distinction is often made between micro‐and nanoparticles, being …

Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …

We report a new process of making highly-porous large polymeric microparticles for local
drug delivery to the lungs by inhalation. Poly (lactic-co-glycolic acid)(PLGA) microparticles …

This thoroughly revised and expanded reference provides authoritative discussions on the
physiologic, pharmacologic, metabolic, molecular, cellular and physicochemical factors …

Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there
were only 19 biotechology medicines on the market. Currently there are more than 100, with …

Purpose. To study the dispersion performance of non-porous corrugated particles, with a
focus on the effect of particle surface morphology on aerosolization of bovine serum albumin …