[HTML][HTML] Nanotechnology-based drug delivery for central nervous system disorders

TT Nguyen, TTD Nguyen, TK Vo, MK Nguyen… - Biomedicine & …, 2021 - Elsevier
Drug delivery to central nervous system (CNS) diseases is very challenging since the
presence of the innate blood–brain barrier (BBB) and the blood-cerebrospinal fluid barrier …

Controlled release and targeted drug delivery with poly (lactic-co-glycolic acid) nanoparticles: reviewing two decades of research

A Zeb, M Gul, TTL Nguyen, HJ Maeng - Journal of Pharmaceutical …, 2022 - Springer
Background Controlled release and targeted delivery of the drug payload are the two most
fascinating applications of nanoparticle-based systems explored in the recent past. The …

[HTML][HTML] Advances in developing therapeutic strategies for Alzheimer's disease

TT Nguyen, TTD Nguyen, TKO Nguyen, TK Vo - Biomedicine & …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive deterioration of brain function, initially
characterized by cognitive deficits, with loss of recent memory and language ability …

Innovative therapies and nanomedicine applications for the treatment of Alzheimer's disease: a state-of-the-art (2017–2020)

A Binda, C Murano, I Rivolta - International Journal of …, 2020 - Taylor & Francis
The field of nanomedicine is constantly expanding. Since the first work dated in 1999, almost
28 thousand articles have been published, and more and more are published every year …

[HTML][HTML] Peptide nano-blanket impedes fibroblasts activation and subsequent formation of pre-metastatic niche

Y Zhou, P Ke, X Bao, H Wu, Y Xia, Z Zhang… - Nature …, 2022 - nature.com
There is evidence to suggest that the primary tumor induces the formation of a pre-metastatic
niche in distal organs by stimulating the production of pro-metastatic factors. Given the …

[HTML][HTML] Tunneling nanotubes: a new target for nanomedicine?

I Ottonelli, R Caraffi, G Tosi, MA Vandelli… - International Journal of …, 2022 - mdpi.com
Tunneling nanotubes (TNTs), discovered in 2004, are thin, long protrusions between cells
utilized for intercellular transfer and communication. These newly discovered structures …

[HTML][HTML] Recent advances on surface-modified GBM targeted nanoparticles: targeting strategies and surface characterization

F Rodà, R Caraffi, S Picciolini, G Tosi… - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common malignant brain tumor, associated with
low long-term survival. Nanoparticles (NPs) developed against GBM are a promising …

[HTML][HTML] Tunneling Nanotube: An Enticing Cell–Cell Communication in the Nervous System

S Dagar, S Subramaniam - Biology, 2023 - mdpi.com
Simple Summary This review highlights the role of tunneling nanotubes (TNTs) and TNT-like
structures in the nervous system. TNTs are thin, hollow plasma membrane projections that …

[HTML][HTML] Quantitative comparison of the protein corona of nanoparticles with different matrices

I Ottonelli, JT Duskey, F Genovese, F Pederzoli… - International Journal of …, 2022 - Elsevier
Nanoparticles (NPs) are paving the way for improved treatments for difficult to treat diseases
diseases; however, much is unknown about their fate in the body. One important factor is the …

[HTML][HTML] Tween® Preserves Enzyme Activity and Stability in PLGA Nanoparticles

JT Duskey, I Ottonelli, A Rinaldi, I Parmeggiani… - Nanomaterials, 2021 - mdpi.com
Enzymes, as natural and potentially long-term treatment options, have become one of the
most sought-after pharmaceutical molecules to be delivered with nanoparticles (NPs); …