Emerging role of pancreatic stellate cell-derived extracellular vesicles in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer that is
characterised by a prominent collagenous stromal reaction/desmoplasia surrounding …
characterised by a prominent collagenous stromal reaction/desmoplasia surrounding …
Single-cell RNA-seq analysis reveals BHLHE40-driven pro-tumour neutrophils with hyperactivated glycolysis in pancreatic tumour microenvironment
L Wang, Y Liu, Y Dai, X Tang, T Yin, C Wang, T Wang… - Gut, 2023 - gut.bmj.com
Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma
(PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune …
(PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune …
Immunomodulatory role of neuropeptides in the cornea
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …
leukocyte populations make it an ideal tissue to study interactions between the nervous and …
The North American Neuroendocrine Tumor Society consensus guidelines for surveillance and management of metastatic and/or unresectable pheochromocytoma …
L Fishbein, J Del Rivero, T Else, JR Howe, SL Asa… - Pancreas, 2021 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the medical management and surveillance of metastatic and …
consensus conference on the medical management and surveillance of metastatic and …
Nucleic acid cancer vaccines targeting tumor related angiogenesis. Could mRNA vaccines constitute a game changer?
S Tadic, A Martínez - Frontiers in Immunology, 2024 - frontiersin.org
Tumor related angiogenesis is an attractive target in cancer therapeutic research due to its
crucial role in tumor growth, invasion, and metastasis. Different agents were developed …
crucial role in tumor growth, invasion, and metastasis. Different agents were developed …
Adrenomedullin–new perspectives of a potent peptide hormone
R Schönauer, S Els‐Heindl… - Journal of Peptide …, 2017 - Wiley Online Library
Adrenomedullin (ADM) is a 52‐amino acid multifunctional peptide, which belongs to the
calcitonin gene‐related peptide (CGRP) superfamily of vasoactive peptide hormones. ADM …
calcitonin gene‐related peptide (CGRP) superfamily of vasoactive peptide hormones. ADM …
Bench-to-bedside pharmacology of adrenomedullin
J Kato, K Kitamura - European journal of pharmacology, 2015 - Elsevier
The bioactive peptide adrenomedullin (AM) exerts pleiotropic actions in various organs and
tissues. In the heart, AM has an inhibitory effect on ventricular remodeling, suppressing …
tissues. In the heart, AM has an inhibitory effect on ventricular remodeling, suppressing …
Targeting adrenomedullin in oncology: A feasible strategy with potential as much more than an alternative anti-angiogenic therapy
R Vázquez, ME Riveiro, C Berenguer-Daize… - Frontiers in …, 2021 - frontiersin.org
The development, maintenance and metastasis of solid tumors are highly dependent on the
formation of blood and lymphatic vessels from pre-existing ones through a series of …
formation of blood and lymphatic vessels from pre-existing ones through a series of …
HIF-dependent mechanisms of relationship between hypoxia tolerance and tumor development
DS Dzhalilova, OV Makarova - Biochemistry (Moscow), 2021 - Springer
Oxygen deficiency is one of the key pathogenetic factors determining development and
severity of many diseases, including inflammatory, infectious diseases, and cancer. Lack of …
severity of many diseases, including inflammatory, infectious diseases, and cancer. Lack of …
Peptidergic systems and cancer: Focus on tachykinin and calcitonin/calcitonin gene-related peptide families
ML Sánchez, FD Rodríguez, R Coveñas - Cancers, 2023 - mdpi.com
Simple Summary Neurokinins A and B, adrenomedullin, adrenomedullin 2, amylin, and
calcitonin gene-related peptide are essential in different tumors. These peptides are …
calcitonin gene-related peptide are essential in different tumors. These peptides are …