Rotaxanes are an emerging class of molecules composed of two building blocks:
macrocycles and threads. Rotaxanes, and their pseudorotaxane and polyrotaxane relatives …

The controlled transport of molecular and ionic substrates across bilayer membranes is a
fundamental task for the operation of living organisms. It is also a highly fascinating and …

Measurements on single molecules can sometimes reveal features that can be difficult to
detect using techniques that probe the averaged properties of many molecules. Here, we …

This perspective explores the idea of using mechanical bonds in the design and
construction of metal-organic framework (MOF) materials. We provide examples of how and …

Mechanically-interlocked molecules (MIMs) are at the basis of artificial molecular machines
and are attracting increasing interest for various applications, from catalysis to drug delivery …

We recently introduced rotaxane-based supramolecular mechanophores that are composed
of a cyclic molecule featuring a luminophore, which is threaded onto an axle molecule that …

A molecular shuttle consisting of a dibenzo-24-crown-8 macrocycle and an axle with two
degenerate peripheral triazolium stations, a central dibenzyl ammonium station, and two …

Summary An H-shaped [2] rotaxane with a biphenyl axle and a 24-crown-8 (24C8)
macrocycle was inserted into the tetrahedral cavities of the isostructural fcu MOFs PCN-57 …

A new [2] rotaxane molecular shuttle linker based on the binding of a 24-crown-8 ether
macrocycle at a benzimidazole recognition site was synthesised. The shuttling dynamics of …

Molecular machines enable external control of structural and dynamic phenomena at the
atomic level. To efficiently transfer their tunable properties into designated functionalities, a …