Oxidative stress modulating nanomaterials and their biochemical roles in nanomedicine

KD Patel, Z Keskin-Erdogan, P Sawadkar… - Nanoscale …, 2024 - pubs.rsc.org
Many pathological conditions are predominantly associated with oxidative stress, arising
from reactive oxygen species (ROS); therefore, the modulation of redox activities has been a …

Strategies for optimizing the soft tissue seal around osseointegrated implants

MN Abdallah, Z Badran, O Ciobanu… - Advanced …, 2017 - Wiley Online Library
Percutaneous and permucosal devices such as catheters, infusion pumps, orthopedic, and
dental implants are commonly used in medical treatments. However, these useful devices …

Design features of implants for direct skeletal attachment of limb prostheses

M Pitkin - Journal of biomedical materials research Part A, 2013 - Wiley Online Library
In direct skeletal attachment (DSA) of limb prostheses, a construct is implanted into an
amputee's residuum bone and protrudes out of the residuum's skin. This technology …

Methods for implant acceptance and wound healing: material selection and implant location modulate macrophage and fibroblast phenotypes

A Boddupalli, L Zhu, KM Bratlie - Advanced Healthcare …, 2016 - Wiley Online Library
This review focuses on materials and methods used to induce phenotypic changes in
macrophages and fibroblasts. Herein, we give a brief overview on how changes in …

Soft and Hard Tissue Integration around Percutaneous Bone-Anchored Titanium Prostheses: Toward Achieving Holistic Biointegration

S Shrivas, H Samaur, V Yadav… - ACS Biomaterials Science …, 2024 - ACS Publications
A holistic biointegration of percutaneous bone-anchored metallic prostheses with both hard
and soft tissues dictates their longevity in the human body. While titanium (Ti) has nearly …

Modulation of macrophage function by bioactive wound dressings with an emphasis on extracellular matrix-based scaffolds and nanofibrous composites

T He, Y Xiao, Z Guo, Y Shi, Q Tan, Y Huang, H Xie - Pharmaceutics, 2023 - mdpi.com
Bioactive wound dressings that are capable of regulating the local wound microenvironment
have attracted a very large interest in the field of regenerative medicine. Macrophages have …

Antibacterial peptide HHC-36 sustained-release coating promotes antibacterial property of percutaneous implant

Q Miao, JL Sun, F Huang, J Wang, P Wang… - … in Bioengineering and …, 2021 - frontiersin.org
Percutaneous implants are widely used in clinical practice. However, infection is the main
clinical problem of percutaneous implants. Titanium dioxide nanotubes are suitable for …

[HTML][HTML] Comparison In Vitro Study on the Interface between Skin and Bone Cell Cultures and Microporous Titanium Samples Manufactured with 3D Printing …

M Shevtsov, E Pitkin, SE Combs, GVD Meulen… - Nanomaterials, 2024 - mdpi.com
Percutaneous implants osseointegrated into the residuum of a person with limb amputation
need to provide mechanical stability and protection against infections. Although significant …

Role of implantable drug delivery devices with dual platform capabilities in the prevention and treatment of bacterial osteomyelitis

C Billings, DE Anderson - Bioengineering, 2022 - mdpi.com
As medicine advances and physicians are able to provide patients with innovative solutions,
including placement of temporary or permanent medical devices that drastically improve …

An animal model to evaluate skin–implant–bone integration and gait with a prosthesis directly attached to the residual limb

BJ Farrell, BI Prilutsky, RS Kistenberg, JF Dalton IV… - Clinical …, 2014 - Elsevier
Background Despite the number of advantages of bone-anchored prostheses, their use in
patients is limited due to the lack of complete skin–implant integration. The objective of the …