Synthetic biodegradable elastomers, such as polyesters and polyurethanes have
revolutionized biomedical therapeutic strategies and devices. Driven by innovations in …

As a type of elastomeric polymers, non-degradable polyurethanes (PUs) have a long history
of being used in clinics, whereas biodegradable PUs have been developed in recent …

Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be
applied to a broad range of resorbable medical devices. In particular, poly (trimethylene …

Background Intervertebral disc degeneration has an annual worldwide socioeconomic
impact masked as low back pain of over 70 billion euros. This disease has a high …

Synthetic polymers are an important component of biomaterials used as implant materials,
drug delivery devices, and tissue engineering scaffolds or hydrogels. This chapter attempts …

Tissue engineering holds potential in the treatment of intervertebral disc degeneration (IDD).
However, implantation of tissue engineered constructs may cause foreign body reaction and …

Biodegradable polyurethane urea (PUU) elastomers are ideal candidates for fabricating
tissue engineering scaffolds with mechanical properties akin to strong and resilient soft …

Heart diseases, including myocardial infarction (MI) and congestive heart failure (CHF),
have high mortality rates. Both MI and CHF are characterized by cardiac muscle damage …

Biodegradable elastomeric scaffolds are of increasing interest for applications in soft tissue
repair and regeneration, particularly in mechanically active settings. The rate at which such …

Annulus fibrosus (AF) tissue engineering has recently received increasing attention as a
treatment for intervertebral disc (IVD) degeneration; however, such engineering remains …