Lipocalin family proteins and their diverse roles in cardiovascular disease

HH Yang, X Wang, S Li, Y Liu, R Akbar… - Pharmacology & …, 2023 - Elsevier
The lipocalin (LCN) family members, a group of small extracellular proteins with 160-180
amino acids in length, can be detected in all kingdoms of life from bacteria to human beings …

Lipocalin-2 as a mediator of neuroimmune communication

R Afridi, JH Kim, A Bhusal, WH Lee… - Journal of Leukocyte …, 2024 - academic.oup.com
Abstract Lipocalin-2, a neutrophil gelatinase-associated lipocalin, is a 25-kDa secreted
protein implicated in a broad range of inflammatory diseases affecting the brain and …

Fetal hypoplastic lungs have multilineage inflammation that is reversed by amniotic fluid stem cell extracellular vesicle treatment

L Antounians, RL Figueira, B Kukreja, ML Litvack… - Science …, 2024 - science.org
Antenatal administration of extracellular vesicles from amniotic fluid stem cells (AFSC-EVs)
reverses features of pulmonary hypoplasia in models of congenital diaphragmatic hernia …

The regulation of TRPA1 expression and function by Th1 and Th2-type inflammation in human A549 lung epithelial cells

S Luostarinen, M Hämäläinen, A Pemmari… - Inflammation …, 2023 - Springer
Abstract Background Transient Receptor Potential Ankyrin 1 (TRPA1) is a cation channel
that mediates pain, itch, cough, and neurogenic inflammation in response to pungent …

Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1-Deficient Mice

JC Kessel, R Weiskirchen, SK Schröder - International Journal of …, 2023 - mdpi.com
Estrogen receptor alpha (ERα) is widely expressed in reproductive organs, but also in non-
reproductive tissues of females and males. There is evidence that lipocalin 2 (LCN2), which …

Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling …

H Zhao, P Wang, X Wang, W Du, HH Yang… - Cardiovascular …, 2023 - academic.oup.com
Aims Systemic inflammation occurs commonly during many human disease settings and
increases vascular permeability, leading to organ failure, and lethal outcomes. Lipocalin 10 …

[HTML][HTML] The impact of the endocrine and immunological function of adipose tissue on Reproduction in women with obesity

K Mączka, O Stasiak, P Przybysz… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Obesity, which leads to metabolic dysregulation and body function impairment, emerges as
one of the pressing health challenges worldwide. Excessive body fat deposits comprise a …

Sex differences in the tumor promoting effects of tobacco smoke in a cRaf transgenic lung cancer disease model

S Zhong, J Borlak - Archives of Toxicology, 2024 - Springer
Tobacco smoke (TS) is the leading cause for lung cancer (LC), and female smokers are at a
greater risk for LC. Yet, the underlying causes are unknown. We performed whole genome …

Increased lipocalin-2 expression in pulmonary inflammation and fibrosis

A Galaris, D Fanidis, E Tsitoura… - Frontiers in …, 2023 - frontiersin.org
Introduction Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive interstitial lung
disease with dismal prognosis. The underlying pathogenic mechanisms are poorly …

The emerging role of bone-derived hormones in diabetes mellitus and diabetic kidney disease

Y Li, Z Gu, J Wang, Y Wang, X Chen… - Frontiers in …, 2022 - frontiersin.org
Diabetic kidney disease (DKD) causes the greatest proportion of end-stage renal disease
(ESRD)–related mortality and has become a high concern in patients with diabetes mellitus …