Bioactivity, cytotoxicity, and molecular modeling studies of novel sulfonamides as dual inhibitors of carbonic anhydrases and acetylcholinesterase

Ö Güleç, C Türkeş, M Arslan, Y Demir, B Dincer… - Journal of Molecular …, 2024 - Elsevier
In the present medical epoch, the prevailing approach of drug discovery, which focuses on
inhibiting a single target, has been superseded by the concept of designing drugs that target …

Tetralone scaffolds and their potential therapeutic applications

B Gauni, K Mehariya, A Shah… - Letters in Drug Design …, 2021 - ingentaconnect.com
Substituted tetralones have played a substantial role in organic synthesis due to their strong
reactivity and suitability as a starting material for a range of synthetic heterocyclic …

Novel turn-on fluorescence sensor for detection and imaging of endogenous H2S induced by sodium nitroprusside

L Wang, W Yang, Y Song, Y Hu - … Acta Part A: Molecular and Biomolecular …, 2020 - Elsevier
Currently, fluorescence analysis method has a good application in the detection and
imaging of biomarkers and has become an important analytical method. Although there are …

Exploration of chalcones and related heterocycle compounds as ligands of adenosine receptors: therapeutics development

C Matthee, G Terre'Blanche, LJ Legoabe… - Molecular Diversity, 2022 - Springer
Adenosine receptors (ARs) are ubiquitously distributed throughout the mammalian body
where they are involved in an extensive list of physiological and pathological processes that …

Chemodivergent photocatalytic access to 1-pyrrolines and 1-tetralones involving switchable C(sp3)–H functionalization

S Tu, Z Qi, W Li, S Zhang, Z Zhang, J Wei… - Frontiers in …, 2022 - frontiersin.org
A chemodivergent photocatalytic approach to 1-pyrrolines and 1-tetralones from alkyl
bromides and vinyl azides has been developed through chemoselectively controllable …

Enantioenriched 1-tetralones via rhodium-catalyzed arylative cascade desymmetrization/acylation of alkynylmalonates

A Selmani, S Darses - Organic letters, 2019 - ACS Publications
An efficient atom-economic rhodium-catalyzed asymmetric arylative cyclization to access
enantioenriched 1-tetralones, bearing a quaternary carbon stereocenter, is described …

Crystal structure of (E)-7-bromo-2-(4-methoxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one, C18H15BrO2

YL Zhang, SL Liu, GG Hou, XF Zhang… - … New Crystal Structures, 2022 - degruyter.com
Crystal structure of (E)-7-bromo-2-(4-methoxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one,
C18H15BrO2 Skip to content Should you have institutional access? Here's how to get it ... De …

Methoxy substituted 2-benzylidene-1-indanone derivatives as A 1 and/or A 2A AR antagonists for the potential treatment of neurological conditions

HDJ van Rensburg, LJ Legoabe, G Terre'Blanche… - …, 2019 - pubs.rsc.org
A prior study reported on hydroxy substituted 2-benzylidene-1-indanone derivatives as A1
and/or A2A antagonists for the potential treatment of neurological conditions. A lead …

(2E)-2-(4-ethoxybenzylidene)-3, 4-dihydro-2H-naphthalen-1-one single crystal: Synthesis, growth, crystal structure, spectral characterization, biological evaluation and …

N Afsar, DR Jonathan, BK Revathi, D Satheesh… - Journal of Molecular …, 2021 - Elsevier
A new α-Tetralone based chalcone compound,(2E)-2-(4-ethoxybenzylidene)-3, 4-dihydro-
2H-naphthalen-1-one (EBDN) has been synthesized by Claisen–Schmidt condensation …

2–Benzylidene–1–Indanone Analogues as Dual Adenosine A1/A2a receptor antagonists for the potential treatment of neurological conditions

HDJ van Rensburg, LJ Legoabe… - Drug …, 2019 - thieme-connect.com
Previous studies explored 2-benzylidine-1-tetralone derivatives as innovative adenosine A 1
and A 2A receptor antagonists for alternative non-dopaminergic treatment of Parkinson's …