To define the systemic neuroimmune interactions in health and disease, we recently
suggested immunoception as a term that refers to the existence of bidirectional functional …

The broad role of stress in the brain-gut axis is widely acknowledged, with implications for
multiple prevalent health conditions that are characterized by chronic gastrointestinal …

Irritable bowel syndrome (IBS) is a functional syndrome characterized by chronic abdominal
pain accompanied by altered bowel habits. Although generally considered a functional …

Chronic visceral pain syndromes are important clinical problems with largely unmet medical
needs. Based on the common overlap with other chronic disorders of visceral or somatic …

Despite recent advances, there is still a major need to better understand the interactions
between brain function and chronic gut inflammation and its clinical implications. Alterations …

Central sensitivity syndromes are characterized by distressing symptoms, such as pain and
fatigue, in the absence of clinically obvious pathology. The scientific underpinnings of these …

Most gastrointestinal diseases and disorders (GIDD) are associated with depression,
anxiety, and cognitive dysfunction. This suggests that shared features of GIDD, particularly …

Abstract Background: Whether Crohn's disease [CD] is correlated with brain structural
changes is unclear. This study examined changes in grey matter [GM] structures in CD …

Background A growing number of neuroimaging studies suggest distinct neural changes in
inflammatory bowel diseases (IBDs). Whether such changes may show similar spatial …

In June 2016, the National Institutes of Health hosted a workshop on functional bowel
disorders (FBDs), particularly irritable bowel syndrome, with the objective of elucidating …