Triple-negative breast cancer (TNBC) is the most complex, aggressive and fatal subtype of
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …

Triple‐negative breast cancer (TNBC) is a subgroup of 15%‐20% of diagnosed breast
cancer patients. It is generally considered to be the most difficult breast cancer subtype to …

Targeted drugs have changed cancer treatment but are often ineffective in the long term
against solid tumours, largely because of the activation of heterogeneous oncogenic …

Pin1 is the only known peptidyl-prolyl cis–trans isomerase (PPIase) that specifically
recognizes and isomerizes the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) …

Constitutive activation of the Hedgehog (Hh) signaling pathway is associated with increased
risk of developing several malignancies. The biological and pathogenic importance of Hh …

For several decades, surface grafted polyethylene glycol (PEG) has been a go-to strategy for
preserving the synthetic identity of liposomes in physiological milieu and preventing …

The prolyl isomerase PIN1, a critical modifier of multiple signalling pathways, is
overexpressed in the majority of cancers and its activity strongly contributes to tumour …

All-Trans Retinoic Acid (ATRA) is the most active metabolite of vitamin A. It is critically
involved in the regulation of multiple processes, such as cell differentiation and apoptosis …

Notch3 is one of four mammalian Notch proteins, which act as signalling receptors to control
cell fate in many developmental and adult tissue contexts. Notch signalling continues to be …

Abstract Treatment of multiple myeloma (MM) cells with sublethal doses of genotoxic drugs
leads to senescence and results in increased NK cell recognition and effector functions …