Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

RNA modifications, known as the “epitranscriptome”, represent a key layer of regulation that
influences a wide array of biological processes in mesenchymal stem cells (MSCs). These …

A call for direct sequencing of full-length RNAs to identify all modifications | Nature Genetics
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The alphabet of building blocks for RNA molecules is much larger than the standard four
nucleotides. The diversity is achieved by the post-transcriptional biochemical modification of …

Disruption of the epigenetic program of gene expression is a hallmark of cancer that initiates
and propagates tumorigenesis. Altered DNA methylation, histone modifications and ncRNAs …

MicroRNAs (miRNAs) are widely present in many organisms and regulate the expression of
genes in various biological processes such as cell differentiation, metabolism, and …

It is well known that the stability of RNA, the interaction between RNA and protein, and the
correct translation of protein are significant forces that drive the transition from normal cell to …

Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in
ensuring cell functions and proper organism development by interacting with cellular …

A vast wealth of recent research has seen attempts of using microRNA (miRNA) found in
biological fluids in clinical research and medicine. One of the reasons behind this trend is …