Exosome composition and seminal plasma proteome: A promising source of biomarkers of male infertility

L Candenas, R Chianese - International journal of molecular sciences, 2020 - mdpi.com
Infertility has become a global health issue, with approximately 50% of infertility cases
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …

Semen proteomics and male infertility

M Jodar, A Soler-Ventura, R Oliva… - Journal of …, 2017 - Elsevier
Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …

Proteomic landscape of seminal plasma associated with dairy bull fertility

AGA Viana, AMA Martins, AH Pontes, W Fontes… - Scientific Reports, 2018 - nature.com
Male fertility is the ability of sperm to fertilize the egg and sustain embryo development.
Several factors determine the fertilizing capacity of mammalian sperm, including those …

Understanding the seminal plasma proteome and its role in male fertility

M Camargo, P Intasqui, RP Bertolla - Basic and clinical andrology, 2018 - Springer
Seminal plasma is a complex fluid comprised of secretions from the seminal vesicles, the
prostate, bulbourethral glands and from the seminiferous tubule lumen/epididymides/vasa …

Proteomics and metabolomics—Current and future perspectives in clinical andrology

MK Panner Selvam, R Finelli, A Agarwal… - Andrologia, 2021 - Wiley Online Library
Proteomics and metabolomics are emerging as promising tools to investigate the molecular
mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in …

Microfluidics facilitating the use of small extracellular vesicles in innovative approaches to male infertility

DM Goss, SA Vasilescu, G Sacks, DK Gardner… - Nature Reviews …, 2023 - nature.com
Sperm are transcriptionally and translationally quiescent and, therefore, rely on the seminal
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …

Proteomic analyses of human sperm cells: understanding the role of proteins and molecular pathways affecting male reproductive health

A Agarwal, MK Panner Selvam, S Baskaran - International Journal of …, 2020 - mdpi.com
Human sperm proteomics research has gained increasing attention lately, which provides
complete information about the functional state of the spermatozoa. Changes in the sperm …

Proteomics of human spermatozoa

J Castillo, A de la Iglesia, M Leiva, M Jodar… - Human …, 2023 - academic.oup.com
Proteomic methodologies offer a robust approach to identify and quantify thousands of
proteins from semen components in both fertile donors and infertile patients. These …

Human prostasomes an extracellular vesicle–Biomarkers for male infertility and prostrate cancer: The journey from identification to current knowledge

AS Vickram, HA Samad, SK Latheef… - International journal of …, 2020 - Elsevier
Extracellular vesicles (EVs) are gaining attention among the cell biologists and researchers
over the last two decades. Prostasomes are considered to be (Evs) secreted by prostate …

Alterations in seminal plasma proteomic profile in men with primary and secondary infertility

AD Martins, MK Panner Selvam, A Agarwal… - Scientific reports, 2020 - nature.com
Proteome of seminal plasma provides profound information related to the male reproductive
health. This pilot study was conducted to characterize proteomic profile of seminal plasma …