Metabolic syndrome: updates on pathophysiology and management in 2021

G Fahed, L Aoun, M Bou Zerdan, S Allam… - International journal of …, 2022 - mdpi.com
Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Unraveling the ncRNA landscape that governs colorectal cancer: A roadmap to personalized therapeutics

NM Hamdy, MB Zaki, NI Rizk, NM Abdelmaksoud… - Life Sciences, 2024 - Elsevier
Colorectal cancer (CRC) being one of the most common malignancies, has a significant
death rate, especially when detected at an advanced stage. In most cases, the fundamental …

Elemental evaluation, nutritional analysis, GC-MS analysis and ameliorative effects of Artocarpus communis JRForst. & G.Forst. seeds' phytoconstituents on metabolic syndrome …

AD Ogunlakin, OA Ojo, GA Gyebi… - Journal of …, 2023 - Taylor & Francis
The nutritional as well as beneficial effects of the Artocarpus communis seed on metabolic
syndrome complications have not been studied. In this research, the aim was to investigate …

Association of FTO rs9939609 polymorphism with serum leptin, insulin, adiponectin, and lipid profile in overweight adults

M Mehrdad, S Doaei, M Gholamalizadeh, M Fardaei… - Adipocyte, 2020 - Taylor & Francis
ABSTRACT FTO gene polymorphisms are associated with obesity and food intake. This
study aimed to investigate the association of FTO rs9939609 polymorphism genotypes with …

The multifaceted functions of the Fat mass and Obesity-associated protein (FTO) in normal and cancer cells

S Relier, E Rivals, A David - RNA biology, 2022 - Taylor & Francis
The last decade has seen mRNA modification emerge as a new layer of gene expression
regulation. The Fat mass and obesity-associated protein (FTO) was the first identified eraser …

Common genetic variation in obesity, lipid transfer genes and risk of Metabolic Syndrome: Results from IDEFICS/I. Family study and meta-analysis

R Nagrani, R Foraita, F Gianfagna, L Iacoviello… - Scientific reports, 2020 - nature.com
As the prevalence of metabolic syndrome (MetS) in children and young adults is increasing,
a better understanding of genetics that underlie MetS will provide critical insights into the …

[HTML][HTML] A comprehensive insight and in Silico analysis of CircRNAs in hepatocellular carcinoma: a step toward ncRNA-based precision medicine

RA Youness, HA Hassan, T Abaza, AA Hady… - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are cardinal players in numerous physiological and pathological
processes. CircRNAs play dual roles as tumor suppressors and oncogenes in different …

Association of FTO, ABCA1, ADRB3, and PPARG variants with obesity, type 2 diabetes, and metabolic syndrome in a Northwest Mexican adult population

J Velazquez-Roman, UA Angulo-Zamudio… - Journal of Diabetes and …, 2021 - Elsevier
Aim To identify associations among allelic variants of the genes FTO, ABCA1, ADRB3, and
PPARG with anthropometric and biochemical traits, metabolic diseases (obesity, T2D or …

Revealing Edible Bird Nest as Novel Functional Foods in Combating Metabolic Syndrome: Comprehensive In Silico, In Vitro, and In Vivo Studies

HK Permatasari, QI Permatasari, NA Taslim, D Subali… - Nutrients, 2023 - mdpi.com
Metabolic dysfunction, which includes intra-abdominal adiposity, glucose intolerance,
insulin resistance, dyslipidemia, and hypertension, manifests into metabolic syndrome and …

The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population

M Saber-Ayad, S Manzoor, H Radwan… - PLoS …, 2019 - journals.plos.org
Background The risk of obesity is determined by complex interactions between genetic and
environmental factors. Little research to date has investigated the interaction between gene …