The combination of procalcitonin and C-reactive protein or presepsin alone improves the accuracy of diagnosis of neonatal sepsis: a meta-analysis and systematic …

L Ruan, GY Chen, Z Liu, Y Zhao, GY Xu, SF Li, CN Li… - Critical Care, 2018 - Springer
Background Sepsis is an important cause of neonatal morbidity and mortality; therefore, the
early diagnosis of neonatal sepsis is essential. Method Our aim was to compare the …

Presepsin for the diagnosis of neonatal early-onset sepsis: a systematic review and meta-analysis

C Poggi, E Lucenteforte, D Petri, S De Masi… - JAMA …, 2022 - jamanetwork.com
Importance Neonatal early-onset sepsis (EOS) is a severe disease, particularly in preterm
infants. Timely diagnosis can be challenging owing to unspecific presentation and …

Biomarkers of neonatal sepsis: where we are and where we are going

G Boscarino, R Migliorino, G Carbone, G Davino… - Antibiotics, 2023 - mdpi.com
Neonatal sepsis is a bacterial bloodstream infection leading to severe clinical manifestations
frequently associated with death or irreversible long-term deficits. Antibiotics are the drug of …

The emerging role of presepsin (P-SEP) in the diagnosis of sepsis in the critically ill infant: a literature review

C Maddaloni, DU De Rose, A Santisi, L Martini… - International journal of …, 2021 - mdpi.com
Sepsis causes high rates of morbidity and mortality in NICUs. The estimated incidence
varies between 5 and 170 per 1000 births, depending on the social context. In very low birth …

The diagnostic accuracy of presepsin in neonatal sepsis: a meta-analysis

I Bellos, G Fitrou, V Pergialiotis, N Thomakos… - European journal of …, 2018 - Springer
There is growing evidence that presepsin is a promising biomarker in the diagnosis of
sepsis in adults. The objective of our study is to investigate current evidence related to the …

[HTML][HTML] Validity of biomarkers in screening for neonatal sepsis–a single center–hospital based study

NI Rashwan, MH Hassan, ZMM El-Deen… - Pediatrics & …, 2019 - Elsevier
Background The diagnosis of neonatal sepsis still considered to be a challenge for both
clinicians and the laboratory due to the non-specific clinical presentations. The present study …

Perinatal presepsin assessment: a new sepsis diagnostic tool?

V Botondi, E D'Adamo, M Plebani… - Clinical Chemistry and …, 2022 - degruyter.com
Perinatal sepsis constitutes a medical emergency and is still one of the major causes of
mortality and morbidity. The possibility of an early diagnosis of sepsis is still debated and …

Soluble CD14 subtype (sCD14-ST) as biomarker in neonatal early-onset sepsis and late-onset sepsis: a systematic review and meta-analysis

I van Maldeghem, CM Nusman, DH Visser - BMC immunology, 2019 - Springer
Background Early diagnosis of bacterial sepsis in neonates is hampered by non-specific
symptoms and the lack of rapid responding laboratory measures. The biomarker soluble …

Accuracy of presepsin in neonatal sepsis: Systematic review and meta-analysis

N Parri, G Trippella, C Lisi, M De Martino… - Expert Review of Anti …, 2019 - Taylor & Francis
Introduction: Neonatal sepsis represents a major cause of morbidity and mortality in
neonates. No diagnostic test has been demonstrated to be sufficiently accurate to confirm or …

Utility of presepsin, soluble triggering receptor expressed on myeloid cells-1, and neutrophil CD64 for early detection of neonatal sepsis

AA El-Madbouly, AA El Sehemawy… - Infection and drug …, 2019 - Taylor & Francis
Background Neonatal sepsis (NS) is an important cause of morbidity and mortality among
newborns. Its diagnosis depends mainly on blood culture that takes at least 48 hours to give …