Despite tremendous successes in the field of antibiotic discovery seen in the previous
century, infectious diseases have remained a leading cause of death. More specifically …

Biological nanopores have been at the focus of numerous studies due to their role in many
biological processes as well as their (prospective) technological applications. Among many …

The outer membrane (OM) of Gram-negative (G−) bacteria presents a barrier for many
classes of antibacterial agents. Lipopolysaccharide (LPS), present in the outer leaflet of the …

The voltage-dependent transport through biological and artificial nanopores is being used in
many applications such as DNA or protein sequencing and sensing. The primary approach …

Gram-negative bacteria cause the majority of highly drug-resistant bacterial infections. To
cross the outer membrane of the complex Gram-negative cell envelope, antibiotics permeate …

In solution, amphoteric compounds exist in anionic, uncharged, zwitterionic and cationic
forms. The importance of zwitterionic drugs is currently under‐represented in the literature …

The permeation of (neutral) molecules through nanopores in the presence of external
voltages depends on several factors including pore electrostatics, electrophoretic force, and …

Modern medicine relies upon antibiotics, but we have arrived to the point where our inability
to come up with new effective molecules against resistant pathogens, together with the …

We propose a new model-free segmentation method, JULES, which combines recent
statistical multiresolution techniques with local deconvolution for idealization of ion channel …

Vibrio parahaemolyticus can cause acute gastroenteritis, wound infections, and septicemia
in humans. The overuse of antibiotics in aquaculture may lead to a high incidence of the …