Clinical aspects of snakebite envenoming and its treatment in low-resource settings

DA Warrell, DJ Williams - The Lancet, 2023 - thelancet.com
There is increasing recognition of the public health importance of snakebite envenoming.
Worldwide annual incidence is likely to be 5 million bites, with mortality exceeding 150 000 …

Broadening the research landscape in the field of snakebite envenoming: Towards a holistic perspective

JM Gutiérrez, I Bolon, J Borri, RR de Castañeda - Toxicon, 2023 - Elsevier
Snakebite envenoming (SBE) is a neglected tropical disease that kills and maims hundreds
of thousands of people yearly, particularly in impoverished rural settings of the Global South …

A long-term observational study of paediatric snakebite in Kilifi County, south-east Kenya

M Abouyannis, M Boga, D Amadi, N Ouma… - PLoS neglected …, 2023 - journals.plos.org
Introduction Estimates suggest that one-third of snakebite cases in sub-Saharan Africa affect
children. Despite children being at a greater risk of disability and death, there are limited …

[HTML][HTML] Improving in vivo assays in snake venom and antivenom research: A community discussion

AE Marriott, NR Casewell, E Lilley, JM Gutiérrez… - …, 2024 - ncbi.nlm.nih.gov
On the 26 th January 2023, a free to attend,'improving in vivo snake venom research: a
community discussion'meeting was held virtually. This webinar brought together researchers …

Oral and IV Varespladib Rescue Experiments in Juvenile Pigs with Weakness Induced by Australian and Papuan Oxyuranus scutellatus Venoms

LL Gilliam, J Gilliam, SP Samuel, RW Carter, J Ritchey… - Toxins, 2023 - mdpi.com
Antivenom is currently the standard-of-care treatment for snakebite envenoming, but its
efficacy is limited by treatment delays, availability, and in many cases, species specificity …

[HTML][HTML] Snakebite-Associated Infections: A Systematic Review and Meta-Analysis

DK Bonilla-Aldana, JL Bonilla-Aldana… - The American Journal …, 2024 - ncbi.nlm.nih.gov
Snakebites still constitute a significant public health problem in developing countries and
are considered a neglected tropical condition by the WHO. Snake accidents are associated …

Cold Finger: Raynaud Phenomenon Following Snakebite Envenoming by Nikolsky's Viper (Vipera berus nikolskii)

O Zinenko, DM Durkin, RW Carter, B Ritter, MR Lewin - Toxins, 2023 - mdpi.com
A field biologist was bitten by a female Nikolsky's viper (Vipera berus nikolskii) in Kharkiv
Oblast, Ukraine. Two months later, the patient began to experience cold-induced vasospasm …

The role of venom proteomics and single-domain antibodies for antivenoms: Progress in snake envenoming treatment

ACM Marinho, A Chapeaurouge, BM Dutra… - Drug Discovery …, 2024 - Elsevier
Highlights•Snake venom proteomics could be a key part of developing high-affinity
nanobodies.•VHH and constructs have become important tools for snakebite …

Landscape of toxin-neutralizing therapeutics for snakebite envenoming (2015–2022): Setting the stage for an R&D agenda

J Borri, JM Gutiérrez, C Knudsen… - PLoS neglected …, 2024 - journals.plos.org
Background Progress in snakebite envenoming (SBE) therapeutics has suffered from a
critical lack of data on the research and development (R&D) landscape. A database …

Development of a core outcome set for use in research evaluations of interventions for venous leg ulceration: International eDelphi consensus

S Hallas, EA Nelson, S O'Meara, G Gethin… - Journal of Tissue …, 2024 - Elsevier
Introduction Venous leg ulceration (VLU) is a chronic, recurring condition with associated
pain, malodour, impaired mobility and susceptibility to infection which in turn significantly …