Despite mixed findings, increasing evidence suggests that people with first-episode
psychosis (FEP) show increased pro-inflammatory and pro-oxidative status. We used the …

Despite significant advances in pharmacological and non-pharmacological treatments,
mood disorders remain a significant source of mental capital loss, with high rates of …

Background In the last decade, there has been growing evidence that an interaction exists
between inflammation and the kynurenine pathway in schizophrenia. Additionally, many …

People with psychotic disorders can show marked interindividual variations in the onset of
illness, responses to treatment and relapse, but they receive broadly similar clinical care …

Neurological, neurodegenerative, and psychiatric disorders represent a serious burden
because of their increasing prevalence, risk of disability, and the lack of effective …

Background and Hypothesis A pro-inflammatory phenotype has been related to psychotic
disorders. The neutrophil-lymphocyte ratio (NLR) is an accessible biomarker that could be …

CIBERSAM: Ten years of collaborative translational research in mental disorders CIBERSAM:
Ten years of collaborative translational research in mental disorders Rev Psiquiatr Salud Ment …

Abstract Background and Hypothesis Treatment response to specific antipsychotic
medications is difficult to predict on clinical grounds alone. The current study hypothesizes …

Neurotrophins particularly brain-derived neurotrophic factor (BDNF) and nerve growth factor
(NGF) are crucial modulators in the neurodevelopment and maintenance of central and …

Background Schizophrenia is associated with patterns of aberrant neurobiological circuitry.
The disease complexity is mirrored by multiple biological interactions known to contribute to …