Platelets storage lesion is mainly orchestrated by platelet activating signals during storage.
Reactive oxygen species (ROS) are being considered as important signaling molecules …

Study objective We investigated the coagulation changes that might occur in acute
normovolemic hemodilution (ANH) blood over several hours during cardiac surgery …

BACKGROUND Routine quantification of platelet‐derived extracellular vesicles (PL‐EVs)
may be useful in the quality control (QC) of platelet concentrates (PCs). The aim of this …

Background Early detection of the platelet storage lesion is still a challenge in transfusion
practice. Using flow cytometry, we evaluated the appearance of the storage lesion, based on …

BACKGROUND Sphingosine‐1‐phosphate (S1P) is a bloodborne lipid that regulates
vascular tone and endothelial permeability. S1P concentrations are reduced in critically ill …

In this retrospective cohort study from a large administrative database in this issue of
Hospital Pediatrics, Lang et al 1 examine epidemiologic trends and clinical outcomes of 4 …

BACKGROUND The INTERCEPT Blood System (IBS) for platelets (PLTs) uses a
combination of psoralen and ultraviolet‐A light to inactivate pathogens that may contaminate …

Platelets are small, anucleate cells that circulate in the blood stream and mediate
hemostasis, inflammation, and angiogenesis. Platelet transfusions are used to treat active …

Materials and Methods: In this paired-study, the air bubbles and foam, which develops after
the preparation of the platelet units were excluded from the control units (n= 10), but not from …