Although reactive oxygen species (ROS) such as superoxide, hydrogen peroxide and
hydroxyl radical are generated as the natural byproduct of normal oxygen metabolism, they …

Many placebo controlled trials and meta-analyses evaluated the efficacy of different drugs
for the treatment of inflammatory bowel disease (IBD), including immunosuppressants and …

Purpose The management of perianal fistula in patients with Crohn's disease is an
extremely challenging medical problem as many fistulas do not respond to available …

Objective To examine whether deviation from the standard intention to treat analysis has an
influence on treatment effect estimates of randomised trials. Design Meta-epidemiological …

Rifaximin is a broad spectrum oral antibiotic with antimicrobial activity against Gram-positive
and Gram-negative aerobic and anaerobic bacteria. It is poorly absorbed and thus has a …

Objectives: Diarrhea the second leading cause of death in childhood is caused by a variety
of organisms. Rehydration reduces the risk of death but it is not effective in shortening …

Results Nineteen clinical trials fulfilled the established criteria (5 studies for infliximab vs.
placebo, 6 for each adalimumab or certolizumab vs. placebo and 2 comparing infliximab …

Introduction: Some inflammatory bowel disease (IBD) patients especially those with
refractory Crohn's disease (CD) or relapsing ulcerative colitis (UC) do not respond to current …

Objective To evaluate the clinical efficacy of silymarin in ulcerative colitis (UC) patients.
Methods A randomized double blinded placebo-controlled clinical trial was conducted in 80 …

Escherichia coli is implicated in the pathogenesis of inflammatory bowel disease (IBD).
Rifaximin, a nonabsorbable derivative of rifampin effective against E. coli, improves …