Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Bacteriocins—a viable alternative to antibiotics?

PD Cotter, RP Ross, C Hill - Nature Reviews Microbiology, 2013 - nature.com
Solutions are urgently required for the growing number of infections caused by antibiotic-
resistant bacteria. Bacteriocins, which are antimicrobial peptides produced by certain …

Microcins, gene-encoded antibacterial peptides from enterobacteria

S Duquesne, D Destoumieux-Garzón, J Peduzzi… - Natural product …, 2007 - pubs.rsc.org
Covering 1982 to 2006 Microcins are gene-encoded antibacterial peptides, with molecular
masses below 10 kDa, produced by enterobacteria. They are secreted under conditions of …

Gut microbiota, antibiotic therapy and antimicrobial resistance: a narrative review

B Pilmis, A Le Monnier, JR Zahar - Microorganisms, 2020 - mdpi.com
Antimicrobial resistance is a major concern. Epidemiological studies have demonstrated
direct relationships between antibiotic consumption and emergence/dissemination of …

Ribosome regulation by the nascent peptide

PS Lovett, EJ Rogers - Microbiological reviews, 1996 - Am Soc Microbiol
Studies of bacterial and eukaryotic systems have identified two-gene operons in which the
translation product of the upstream gene influences translation of the downstream gene. The …

The export of the DNA replication inhibitor Microcin B17 provides immunity for the host cell.

MC Garrido, M Herrero, R Kolter, F Moreno - The EMBO journal, 1988 - embopress.org
Microcin B17 (MccB17) is a peptide antibiotic which inhibits DNA replication in
Enterobacteriaceae. Microcin‐producing strains are immune to the action of the microcin …

Lethal effects of apidaecin on escherichia coliinvolve sequential molecular interactions with diverse targets

M Castle, A Nazarian, P Tempst - Journal of Biological Chemistry, 1999 - ASBMB
Apidaecins, short proline-arginine-rich peptides from insects, are highly bactericidal through
a mechanism that includes stereoselective elements but is completely devoid of any pore …

The cyclic structure of microcin J25, a 21‐residue peptide antibiotic from Escherichia coli

A Blond, J Péduzzi, C Goulard… - European journal of …, 1999 - Wiley Online Library
Microcin J25 (MccJ25) is the single representative of the immunity group J of the microcin
group of peptide antibiotics produced by Enterobacteriaceae. It induces bacterial …

Aminoacyl-tRNA synthetase inhibitors as potential antibiotics

GHM Vondenhoff, A Van Aerschot - European journal of medicinal …, 2011 - Elsevier
Increasing resistance to antibiotics is a major problem worldwide and provides the stimulus
for development of new bacterial inhibitors with preferably different modes of action. In …

[HTML][HTML] A novel bacteriocin with a YGNGV motif from vegetable-associated Enterococcus mundtii: full characterization and interaction with target organisms

MHJ Bennik, B Vanloo, R Brasseur, LGM Gorris… - … et Biophysica Acta (BBA …, 1998 - Elsevier
A novel broad-spectrum antimicrobial peptide produced by vegetable-associated
Enterococcus mundtii was purified and characterized, and designated mundticin. To our …