Prophylaxis against upper gastrointestinal bleeding in hospitalized patients

D Cook, G Guyatt - New England Journal of Medicine, 2018 - Mass Medical Soc
Preventing Gastrointestinal Bleeding in the Hospital Acid suppression is widely used to
lower the risk of gastrointestinal bleeding in critically ill patients, and the practice has spread …

Medication-related interventions to improve medication safety and patient outcomes on transition from adult intensive care settings: a systematic review and meta …

RS Bourne, JK Jennings, M Panagioti… - BMJ quality & …, 2022 - qualitysafety.bmj.com
Background Patients recovering from an episode in an intensive care unit (ICU) frequently
experience medication errors on transition to the hospital ward. Structured handover …

Position paper on critical care pharmacy services: 2020 update

I Lat, C Paciullo, MJ Daley, R MacLaren… - Critical care …, 2020 - journals.lww.com
Objectives: To provide a multiorganizational statement to update recommendations for
critical care pharmacy practice and make recommendations for future practice. A position …

Pharmacist avoidance or reductions in medical costs in critically ill adults: PHARM-CRIT study

MA Rech, PK Gurnani, WJ Peppard… - Critical care …, 2021 - journals.lww.com
OBJECTIVES: To comprehensively classify interventions performed by ICU clinical
pharmacists and quantify cost avoidance generated through their accepted interventions …

Optimization of critical care pharmacy clinical services: a gap analysis approach

AS Newsome, B Murray, SE Smith… - American Journal of …, 2021 - academic.oup.com
Every critically ill patient requires care by a critical care pharmacist (CCP) for best possible
outcomes. Indeed, these highly trained professionals generate benefit through direct patient …

[HTML][HTML] Prevention of stress-related ulcer bleeding at the intensive care unit: risks and benefits of stress ulcer prophylaxis

L Buendgens, A Koch, F Tacke - World journal of critical care …, 2016 - ncbi.nlm.nih.gov
Stress-related mucosal disease is a typical complication of critically ill patients in the
intensive care unit (ICU). It poses a risk of clinically relevant upper gastrointestinal (GI) …

Assessing the risk of hospital-acquired Clostridium difficile infection with proton pump inhibitor use: a meta-analysis

V Arriola, J Tischendorf, J Musuuza… - infection control & …, 2016 - cambridge.org
BACKGROUNDClostridium difficile is the principal infectious cause of antibiotic-associated
diarrhea and accounts for 12% of hospital-acquired infections. Recent literature has shown …

Low‐value proton pump inhibitor prescriptions among older adults at a large academic health system

JN Mafi, FP May, KL Kahn, M Chong… - Journal of the …, 2019 - Wiley Online Library
BACKGROUND Older adults are particularly vulnerable to complications from proton pump
inhibitor (PPI) drugs. We sought to characterize the prevalence of potentially low‐value PPI …

Medication regimen complexity is associated with pharmacist interventions and drug‐drug interactions: A use of the novel MRC‐ICU scoring tool

AS Newsome, SE Smith, WJ Olney… - Journal of the …, 2020 - Wiley Online Library
Background Clinical pharmacists are established members of the interprofessional patient
care team, but limited guidance for the optimal utilization of pharmacy resources is available …

Acid-suppressive therapy and risk of infections: pros and cons

L Fisher, A Fisher - Clinical drug investigation, 2017 - Springer
This narrative review summarises the benefits, risks and appropriate use of acid-
suppressing drugs (ASDs), proton pump inhibitors and histamine-2 receptor antagonists …