Microneedles for painless transdermal immunotherapeutic applications

H Amani, MA Shahbazi, C D'Amico, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …

[HTML][HTML] Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications

T Bauleth-Ramos, N El-Sayed, F Fontana, M Lobita… - Materials Today, 2023 - Elsevier
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …

Cubosomes as an emerging platform for drug delivery: A review of the state of the art

MAS Abourehab, MJ Ansari, A Singh… - Journal of Materials …, 2022 - pubs.rsc.org
Lipid-based drug-delivery nanoparticles, including non-lamellar-type, mesophasic
nanostructured materials of lyotropic liquid crystals (LLCs), have been a topic of interest for …

[HTML][HTML] Trends in drug-and vaccine-based dissolvable microneedle materials and methods of fabrication

LE Moore, S Vucen, AC Moore - European Journal of Pharmaceutics and …, 2022 - Elsevier
Microneedle patches, also called microarray patches (MAP), are an emerging technology for
delivery and sampling of drugs, vaccines and other materials. This review focuses on the …

The cubosome-based nanoplatforms in cancer therapy: Seeking new paradigms for cancer theranostics

BHJ Gowda, MG Ahmed, SA Alshehri, S Wahab… - Environmental …, 2023 - Elsevier
Lyotropic liquid crystals are self-assembled, non-lamellar, and mesophase nanostructured
materials that have garnered significant attention as drug carriers. Cubosomes, a subtype of …

Natural Ingredients of Transdermal Drug Delivery Systems as Permeation Enhancers of Active Substances through the Stratum Corneum

N Schafer, R Balwierz, P Biernat… - Molecular …, 2023 - ACS Publications
In recent years, significant progress has been made in transdermal drug delivery systems,
but there is still a search for enhancers that can improve the absorption of active substances …

[HTML][HTML] Recent advances in drug delivery applications of cubosomes, hexosomes, and solid lipid nanoparticles

A Yaghmur, H Mu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The use of lipid nanocarriers for drug delivery applications is an active research area, and a
great interest has particularly been shown in the past two decades. Among different lipid …

[HTML][HTML] Trilayer dissolving polymeric microneedle array loading Rose Bengal transfersomes as a novel adjuvant in early-stage cutaneous melanoma management

S Demartis, QK Anjani, F Volpe-Zanutto… - International Journal of …, 2022 - Elsevier
Melanoma remains a global concern, but current therapies present critical limitations
pointing out the urgent need for novel strategies. Among these, the cutaneous delivery of …

Exploiting unique features of microneedles to modulate immunity

C Edwards, SA Shah, T Gebhardt… - Advanced …, 2023 - Wiley Online Library
Microneedle arrays (MNAs) are small patches containing hundreds of short projections that
deliver signals directly to dermal layers without causing pain. These technologies are of …