Over the past few decades, data-driven machine learning (ML) has distinguished itself from
hypothesis-driven studies and has recently received much attention in environmental …

Three-dimensional (3D) cell cultures, including organ-on-a-chip (OOC) devices, offer the
possibility to mimic human physiology conditions better than 2D models. The organ-on-a …

For the analysis of biological analytes in complex matrices, it is difficult to achieve extraction
of analytes and enrichment in an aqueous–aqueous single-drop microextraction system. In …

Halogenated BPA (XBPA) forms resulting from water chlorination can lead to increased
toxicity and different biological effects. While previous studies have reported the occurrence …

The limited characterization and detection capacity of unknown compounds hinder our
understanding of the molecular composition of toxic compounds in PM2. 5. The present …

Human cell-based population-wide in vitro models have been proposed as a strategy to
derive chemical-specific estimates of inter-individual variability; however, the utility of this …

As part of the development of new approach methodologies (NAMs), numerous in vitro
methods are being developed to characterize the potential toxicity of inhalable xenobiotics …

Steel slags, the main waste product from the steel industry, may have several reuse
possibilities. Among others, building applications represent a crucial field. However, the …

Although humans are continuously exposed to complex chemical mixtures in the
environment, it has been extremely challenging to investigate the resulting cumulative risks …

The evaluation of exposure to multiple contaminants in a mixture presents a number of
challenges. For example, the characterization of chemical metabolism in a mixture setting …