In the last decade, antibody-drug conjugates (ADCs), normally formed by a humanized
antibody and a small drug via a chemical cleavable or non-cleavable linker, have emerged …

A drug conjugate consists of a cytotoxic drug bound via a linker to a targeted ligand,
allowing the targeted delivery of the drug to one or more tumor sites. This approach …

From the last few years mode of interactions between drugs and DNA is an attractive
research area as it bridges chemistry, molecular biology and medicinal science. Interactions …

Natural enediyne antibiotics are powerful DNA-cleavage agents due to the presence of the
highly reactive hex-3-ene-1, 5-diyne units. However, the complicated chemical structure and …

Peptide–drug conjugates (PDCs) are an emerging targeted therapeutic drug following on
from the relative success of antibody–drug conjugates (ADCs). In this class, peptides are …

Antibody–drug conjugates (ADCs) consist of conjugates of monoclonal antibodies to the
desirable cytotoxic payloads via a specific chemical linker. These conjugates could target to …

Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses
important concepts, fundamentals and prospective applications of 'Linker Chemistry'in a …

Natural enediyne antibiotics undergo thermally induced cycloaromatization under
physiological conditions to generate highly reactive diradicals, effectively abstract hydrogen …

El tema que he escogido para este discurso de ingreso es la relación-muy personal y
extendida en el tiempo-que he mantenido con el ácido desoxirribonucleico (ADN) y …