Human pluripotent stem cells (hPSCs) provide powerful resources for application in
regenerative medicine and pharmaceutical development. In the past decade, various …

An important component of tissue engineering (TE) is the supporting matrix upon which cells
and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue …

Continuation of mammalian species requires the formation and development of the sexually
dimorphic germ cells. Cultured embryonic stem cells are generally considered pluripotent …

We report a fully defined synthetic polymer coating, poly [2-(methacryloyloxy) ethyl dimethyl-
(3-sulfopropyl) ammonium hydroxide](PMEDSAH), which sustains long-term human …

Current practices to maintain human pluripotent stem cells (hPSCs), which include induced
pluripotent stem cells and embryonic stem cells, in an undifferentiated state typically depend …

The cardinal motor symptoms of Parkinson's disease (PD) are caused by the vulnerability to
dysfunction and degeneration of ventral midbrain (VM) dopaminergic (DA) neurons. A major …

Organoids are tiny, self-organized, three-dimensional tissue cultures that are derived from
the differentiation of stem cells. The growing interest in the use of organoids arises from their …

Human embryonic stem cells (hESCs) are thought to be a promising cell source for cell
transplantation therapy. For such a clinical application, the hESCs should be manipulated …

The micro-environment in which stem cells reside regulates their fate, and synthetic
materials have recently been designed to emulate these regulatory processes for various …

Pluripotent stem cell lines can be derived from blastocyst embryos, which yield embryonic
stem cell lines (ES cells), as well as the postimplantation epiblast, which gives rise to …