Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

S Qian, O Golubnitschaja, X Zhan - Epma Journal, 2019 - Springer
A strong relationship exists between tumor and inflammation, which is the hot point in cancer
research. Inflammation can promote the occurrence and development of cancer by …

Role of inflammatory mediators, macrophages, and neutrophils in glioma maintenance and progression: mechanistic understanding and potential therapeutic …

AS Basheer, F Abas, I Othman, R Naidu - Cancers, 2021 - mdpi.com
Simple Summary The tumor microenvironment is a complex network comprised of
neoplastic and a variety of immune cells, proteins, and inflammatory mediators. Previous …

[PDF][PDF] Retracted article: significance of the IL-8 pathway for immunotherapy

M Gonzalez-Aparicio, C Alfaro - Human vaccines & …, 2020 - Taylor & Francis
Statement of Retraction We, the Publisher of Human Vaccines & Immunotherapeutics, have
retracted the following article: Manuela Gonzalez-Aparicio and Carlos Alfaro,“Significance of …

Exosomes as novel diagnostic biomarkers and therapeutic tools in gliomas

P Skouras, AN Gargalionis, C Piperi - International Journal of Molecular …, 2023 - mdpi.com
Exosomes constitute small extracellular vesicles that contain lipids, proteins, nucleic acids,
and glycoconjugates from the secreted cells and are capable of transmitting signals …

Dual role of CXCL8 in maintaining the mesenchymal state of glioblastoma stem cells and M2-like tumor-associated macrophages

W Yuan, Q Zhang, D Gu, C Lu, D Dixit, RC Gimple… - Clinical Cancer …, 2023 - AACR
Purpose: The dynamic interplay between glioblastoma stem cells (GSC) and tumor-
associated macrophages (TAM) sculpts the tumor immune microenvironment (TIME) and …

Soluble CD163 changes indicate monocyte association with cognitive deficits in Parkinson's disease

SK Nissen, SA Ferreira, MC Nielsen… - Movement …, 2021 - Wiley Online Library
Background Parkinson's disease (PD) is a neurodegenerative disorder with a significant
immune component, as demonstrated by changes in immune biomarkers in patients' …

Cytokine profile in development of glioblastoma in relation to healthy individuals

P Jarmuzek, P Defort, M Kot… - International Journal of …, 2023 - mdpi.com
Cytokines play an essential role in the control of tumor cell development and multiplication.
However, the available literature provides ambiguous data on the involvement of these …

Immune response in glioma's microenvironment

H Chen, M Li, Y Guo, Y Zhong, Z He, Y Xu… - Innovative surgical …, 2021 - degruyter.com
Objectives Glioma is the most common tumor of the central nervous system. In this review,
we outline the immunobiological factors that interact with glioma cells and tumor …

Tea Polyphenols Protects Tracheal Epithelial Tight Junctions in Lung during Actinobacillus pleuropneumoniae Infection via Suppressing TLR-4/MAPK/PKC-MLCK …

X Li, Z Liu, T Gao, W Liu, K Yang, R Guo, C Li… - International Journal of …, 2023 - mdpi.com
Actinobacillus pleuropneumoniae (APP) is the causative pathogen of porcine
pleuropneumonia, a highly contagious respiratory disease in the pig industry. The …

Understanding the complexity of the tumor microenvironment in K-ras mutant lung cancer: finding an alternative path to prevention and treatment

S Deng, MJ Clowers, WV Velasco… - Frontiers in …, 2020 - frontiersin.org
Kirsten rat sarcoma viral oncogene (K-ras) is a well-documented, frequently mutated gene in
lung cancer. Since K-ras regulates numerous signaling pathways related to cell survival and …