Endocytosis is a process essential to the health and well-being of cell. It is required for the
internalisation and sorting of “cargo”—the macromolecules, proteins, receptors and lipids of …

Epilepsy is a common symptom of many neurological disorders and can lead to neuronal
damage that plays a major role in seizure-related disability. The peptidyl-prolyl isomerase …

In the healthy brain, neuronal excitability and synaptic strength are homeostatically
regulated to keep neuronal network activity within physiological boundaries. Epilepsy is …

Neuronal activity propagates through the network during seizures, engaging brain dynamics
at multiple scales. Such propagating events can be described through the avalanches …

Alzheimer's disease is linked to increased levels of amyloid beta (Aβ) in the brain, but the
mechanisms underlying neuronal dysfunction and neurodegeneration remain enigmatic …

Epilepsy is a neurological disorder characterised by unprovoked, repetitive seizures caused
by abnormal neuronal firing. The Wnt/β–Catenin signalling pathway is involved in seizure …

Neuronal hyperexcitability often results from an unbalance between excitatory and inhibitory
neurotransmission, but the synaptic alterations leading to enhanced seizure propensity are …

Among clinically highly efficient antiseizure medications (ASMs) there are modifiers of the
presynaptic release machinery. Of them, levetiracetam and brivaracetam show a high affinity …

The epileptic brain is the result of a sequence of events transforming normal neuronal
populations into hyperexcitable networks supporting recurrent seizure generation. These …

Autism is a neurodevelopmental disorder, the prevalence of which has increased
dramatically in the United States over the past two decades. It is characterized by …