The gut microbiome has been shown to influence the response of tumors to anti–PD-1
(programmed cell death–1) immunotherapy in preclinical mouse models and observational …

The cell type specific sequences of transcriptional programs during lung regeneration have
remained elusive. Using time-series single cell RNA-seq of the bleomycin lung injury model …

Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor
malignancy and suppresses anti-tumor immunity. The context specificity of AHR target …

This review focuses on neurotrophins and their tyrosine kinase receptors, with an emphasis
on their relevance to the function and dysfunction in the human nervous system. It also deals …

RNA sequencing (RNA-seq) is one of the most widely used technologies in transcriptomics
as it can reveal the relationship between the genetic alteration and complex biological …

Human brain development is underpinned by cellular and molecular reconfigurations
continuing into the third decade of life. To reveal cell dynamics orchestrating neural …

The neocortex contains a multitude of cell types that are segregated into layers and
functionally distinct areas. To investigate the diversity of cell types across the mouse …

Potato is the most widely produced tuber crop worldwide. However, reconstructing the four
haplotypes of its autotetraploid genome remained an unsolved challenge. Here, we report …

There is a significant interest in identifying blood-borne factors that mediate tissue crosstalk
and function as molecular effectors of physical activity. Although past studies have focused …

Genomic reaction norms represent the range of gene expression phenotypes (usually
mRNA transcript levels) expressed by a genotype along an environmental gradient …