CEST, ASL, and magnetization transfer contrast: How similar pulse sequences detect different phenomena

L Knutsson, J Xu, A Ahlgren… - Magnetic resonance in …, 2018 - Wiley Online Library
Chemical exchange saturation transfer (CEST), arterial spin labeling (ASL), and
magnetization transfer contrast (MTC) methods generate different contrasts for MRI …

Sensitivity enhancement by progressive saturation of the proton reservoir: a solid-state NMR analogue of chemical exchange saturation transfer

MJ Jaroszewicz, AR Altenhof… - Journal of the …, 2021 - ACS Publications
Chemical exchange saturation transfer (CEST) enhances solution-state NMR signals of
labile and otherwise invisible chemical sites, by indirectly detecting their signatures as a …

Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids

M Novakovic, Ē Kupče, A Oxenfarth… - Nature …, 2020 - nature.com
Multidimensional TOCSY and NOESY are central experiments in chemical and biophysical
NMR. Limited efficiencies are an intrinsic downside of these methods, particularly when …

Indirectly detected satellite-transition quadrupolar NMR via progressive saturation of the proton reservoir

T Wolf, A Eden-Kossoy, L Frydman - Solid state nuclear magnetic …, 2023 - Elsevier
Static satellite-transitions (ST) NMR line shapes from half-integer quadrupolar nuclei could
be very informative: they can deliver insight about local motions over a wide range of …

Relaxation-Assisted Magnetization Transfer Phenomena for a Sensitivity-Enhanced 2D NMR

M Novakovic, J Kim, XC Su, E Kupče… - Analytical …, 2023 - ACS Publications
2D NOESY and TOCSY play central roles in contemporary NMR. We have recently
discussed how solvent-driven exchanges can significantly enhance the sensitivity of such …

Looped-PROjected SpectroscopY (L-PROSY): A simple approach to enhance backbone/sidechain cross-peaks in 1H NMR

M Novakovic, SF Cousin, MJ Jaroszewicz… - Journal of Magnetic …, 2018 - Elsevier
Cross-relaxation and isotropic mixing phenomena leading to the Nuclear Overhauser Effect
(NOE) and to the TOCSY experiment, lie at the center of structural determinations by NMR …

On the potential of Fourier-encoded saturation transfers for sensitizing solid-state magic-angle spinning NMR experiments

MJ Jaroszewicz, M Novakovic… - The Journal of chemical …, 2022 - pubs.aip.org
Chemical exchange saturation transfer (CEST) is widely used for enhancing the solution
nuclear magnetic resonance (NMR) signatures of magnetically dilute spin pools, in …

Detection of electrostatic molecular binding using the water proton signal

Y Zhou, C Bie, PCM van Zijl, J Xu… - Magnetic resonance …, 2022 - Wiley Online Library
Purpose Saturation transfer MRI has previously been used to probe molecular binding
interactions with signal enhancement via the water signal. Here, we detail the relayed …

Sensitivity Enhancement of Ultra‐Wideline NMR by Progressive Saturation of the Proton Reservoir Under Magic‐Angle Spinning

T Wolf, Y Goobes, L Frydman - ChemPhysChem, 2024 - Wiley Online Library
Solid‐state NMR of low‐γ nuclides is often characterized by low sensitivity and by significant
spectral broadenings induced by the quadrupolar and the chemical‐shift anisotropy …

[HTML][HTML] CEST-based detection of labile protons by ultrafast 2D NMR

RP Martinho, GL Olsen, L Frydman - Journal of Magnetic Resonance Open, 2023 - Elsevier
Chemical exchange saturation transfer (CEST) NMR is widely used for enhancing the
sensitivity of low-abundance exchanging sites in general, and for the water-based detection …