The role of ubiquitination and deubiquitination in cancer metabolism

T Sun, Z Liu, Q Yang - Molecular cancer, 2020 - Springer
Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …

Natural product interventions for chemotherapy and radiotherapy-induced side effects

QY Zhang, FX Wang, KK Jia, LD Kong - Frontiers in pharmacology, 2018 - frontiersin.org
Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy
are the common cancer treatments. However, the development of adverse effects resulting …

Pharmacological and Antioxidant Activities of Rhus coriaria L. (Sumac)

H Alsamri, K Athamneh, G Pintus, AH Eid, R Iratni - Antioxidants, 2021 - mdpi.com
Rhus coriaria L.(Anacardiaceae), commonly known as sumac, is a commonly used spice,
condiment, and flavoring agent, especially in the Mediterranean region. Owing to its …

[HTML][HTML] The interaction mechanism between autophagy and apoptosis in colon cancer

Q Xie, Y Liu, X Li - Translational Oncology, 2020 - Elsevier
Autophagy and apoptosis play crucial roles in tumorigenesis. Recent studies have shown
that autophagy and apoptosis have a cross-talk relationship in anti-tumor therapy. It is well …

Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

H Pan, Y Wang, K Na, Y Wang, L Wang, Z Li… - Cell death & …, 2019 - nature.com
Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …

So many roads: the multifaceted regulation of autophagy induction

AF Corona Velazquez, WT Jackson - Molecular and cellular …, 2018 - Taylor & Francis
Autophagy is an evolutionary conserved, degradative process from single-cell eukaryotes,
such as Saccharomyces cerevisiae, to higher mammals, such as humans. The regulation of …

Rhus coriaria L. (Sumac), a Versatile and Resourceful Food Spice with Cornucopia of Polyphenols

GES Batiha, OM Ogunyemi, HM Shaheen, FR Kutu… - Molecules, 2022 - mdpi.com
In recent years, utilization of Rhus coriaria L.(sumac) is upgrading not only in their culinary
use and human nutrition, but also in the pharmaceutical industry, food industry and …

HMGB1 in the interplay between autophagy and apoptosis in cancer

R Chen, J Zou, X Zhong, J Li, R Kang, D Tang - Cancer Letters, 2023 - Elsevier
Lysosome-mediated autophagy and caspase-dependent apoptosis are dynamic processes
that maintain cellular homeostasis, ensuring cell health and functionality. The intricate …

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma

P Kubatka, M Kello, K Kajo, M Samec… - International journal of …, 2020 - mdpi.com
Comprehensive scientific data provide evidence that isolated phytochemicals or whole plant
foods may beneficially modify carcinogenesis. The aim of this study was to evaluate the …

Carnosol induces p38-mediated ER stress response and autophagy in human breast cancer cells

H Alsamri, A Alneyadi, K Muhammad, MA Ayoub… - Frontiers in …, 2022 - frontiersin.org
We recently reported that carnosol induces ROS-dependent autophagy and apoptosis in
breast cancer cells. We also reported that carnosol inhibits breast cancer cell migration …