Chirality is a ubiquitous feature in living systems. Today, it is widely recognized that many
biologically interesting compounds, such as drugs, agrochemicals, food additives, and …

Chiral resolution is an operation of great interest and increasing importance for the scientific
community and industry. There are two approaches to provide enantiomerically pure …

This work presents a comprehensive insight about simulated moving bed (SMB) technology,
from concept to unit operation and process demonstration. A particular relevance is given to …

The solubility of the racemic solid phase of ketoprofen (KTP) in methanol, ethanol,
isopropanol, butanol, acetonitrile, ethyl acetate, 1, 4-dioxane and toluene has been …

The human body is a chiral environment and many drugs are chiral and interact differently
depending on the type of enantiomer. Therefore, the interest in analytical and preparative …

Obtaining chiral, biologically active compounds in enantio-pure form is one of the great
challenges in the pharmaceutical industry. This work prepared surface molecularly imprinted …

This paper investigates feasibility of xylo-oligosaccharides (XOS) purification by sequential
simulated moving bed (SSMB) that has three sub-steps. Multi-objective optimizations were …

Solubility data are compiled and reviewed for 33 nonsteroidal anti-inflammatory drugs
dissolved in neat organic solvents and in well-defined binary and ternary organic solvents …

The pharmaceutical industry is now directed to the market of more safety and efficient drugs,
based on single enantiomers. Ketoprofen, still used as a racemic pharmaceutical drug …

The separation of nadolol racemates under high pH reversed-phase preparative
chromatography is presented for the first time. Three Waters C18 adsorbents (XBridge …