Acute rejection after liver transplantation with machine perfusion versus static cold storage: a systematic review and meta-analysis

M Maspero, K Ali, B Cazzaniga, S Yilmaz, R Raj… - Hepatology, 2023 - journals.lww.com
Acute rejection after liver transplantation with machine per... : Hepatology Acute rejection after
liver transplantation with machine perfusion versus static cold storage: A systematic review and …

Machine perfusion of the liver and bioengineering

A Schlegel, H Mergental, C Fondevila, RJ Porte… - Journal of …, 2023 - Elsevier
With the increasing number of accepted candidates on waiting lists worldwide, there is an
urgent need to expand the number and the quality of donor livers. Dynamic preservation …

Machine perfusion techniques for liver transplantation-A meta-analysis of the first seven randomized-controlled trials

A Parente, F Tirotta, A Pini, J Eden, D Dondossola… - Journal of …, 2023 - Elsevier
Background & Aims Machine perfusion is increasingly being tested in clinical
transplantation. Despite this, the number of large prospective clinical trials remains limited …

[HTML][HTML] A randomized-controlled trial of ischemia-free liver transplantation for end-stage liver disease

Z Guo, Q Zhao, Z Jia, C Huang, D Wang, W Ju… - Journal of …, 2023 - Elsevier
Background & Aims Ischemia-reperfusion injury (IRI) has thus far been considered as an
inevitable component of organ transplantation, compromising outcomes, and limiting organ …

[HTML][HTML] Normothermic regional perfusion can improve both utilization and outcomes in DCD liver, kidney, and pancreas transplantation

Y Bekki, KP Croome, B Myers, K Sasaki… - Transplantation …, 2023 - journals.lww.com
Background. Normothermic regional perfusion (NRP) has gained widespread adoption in
multiple European countries. The aim of this study was to examine the influence of …

Six-month abdominal transplant recipient outcomes from donation after circulatory death heart donors: a retrospective analysis by procurement technique

A Wall, M Rosenzweig, GJ McKenna, TW Ma… - American Journal of …, 2023 - Elsevier
Standard US practice for donation after circulatory death (DCD) abdominal organ
procurement is superrapid recovery (SRR). A newer approach using thoracoabdominal …

Development of a portable abdominal normothermic regional perfusion (A-NRP) program in the United States

KP Croome, TE Brown, RL Mabrey… - Liver …, 2023 - journals.lww.com
In situ abdominal normothermic regional perfusion (A-NRP) has been used for liver
transplantation (LT) with donation after circulatory death (DCD) liver grafts in Europe with …

Screening for mitochondrial function before use-routine liver assessment during hypothermic oxygenated perfusion impacts liver utilization

J Eden, E Breuer, D Birrer, M Müller, M Pfister… - …, 2023 - thelancet.com
Background To report on a concept of liver assessment during ex situ hypothermic
oxygenated perfusion (HOPE) and its significant impact on liver utilization. Methods An …

Mitochondria and ischemia reperfusion injury

R Panconesi, J Widmer, MF Carvalho… - Current opinion in …, 2022 - journals.lww.com
Mitochondria are attractive targets for novel molecules to limit IRI-associated inflammation.
Although dynamic preservation techniques could serve as delivery tool for new therapeutic …

Machine perfusion for extended criteria donor livers: what challenges remain?

J Widmer, J Eden, MF Carvalho, P Dutkowski… - Journal of Clinical …, 2022 - mdpi.com
Based on the renaissance of dynamic preservation techniques, extended criteria donor
(ECD) livers reclaimed a valuable eligibility in the transplantable organ pool. Being more …