Reactive oxygen species (ROS) play a critical role in defining the functional competence of
human spermatozoa. When generated in moderate amounts, ROS promote sperm …

This article addresses the importance of oxidative processes in both the generation of
functional gametes and the aetiology of defective sperm function. Functionally, sperm …

BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit
the paternal genome to offspring. These highly specialized cells have a unique structure …

Oxidative stress occurs when the levels of reactive oxygen species (ROS) overcome the
antioxidant defenses of the organism, jeopardizing several biological functions, including …

The ability of spermatozoa to generate reactive oxygen species (ROS) has been
appreciated since the 1940s. It is a universal property of mature spermatozoa from all …

Autophagy is an evolutionarily conserved process that plays a crucial role in maintaining a
series of cellular functions. It has been found that autophagy is closely involved in the …

Oxidative stress is an important component of the cytopathology of equine spermatozoa
undergoing storage as liquid or frozen semen. Damage to chromatin, membranes and …

Sperm capacitation can be increased by the addition of reactive oxygen species (ROS) and
decreased by antioxidants. Broadly consistent results have been achieved with a wide …

Capacitation is a remarkable process whereby spermatozoa prepare themselves for
engagement with the oocyte. Although the existence of this process has been appreciated …

This chapter explores the possibility that capacitation and apoptosis are linked processes
joined by their common dependence on the continued generation of reactive oxygen …