Next-generation Vaccine Development with nanomaterials: recent advances, possibilities, and challenges

S Shetty, PC Alvarado, D Pettie… - Annual Review of …, 2024 - annualreviews.org
Nanomaterials are becoming important tools for vaccine development owing to their tunable
and adaptable nature. Unique properties of nanomaterials afford opportunities to modulate …

Mechanisms underlying overactive bladder and interstitial cystitis/painful bladder syndrome

L Grundy, A Caldwell, SM Brierley - Frontiers in neuroscience, 2018 - frontiersin.org
The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

Integrated analysis of lncRNA and circRNA mediated ceRNA regulatory networks in skin reveals innate immunity differences between wild-type and yellow mutant …

S Wu, J Huang, Y Li, Z Liu, L Zhao - Frontiers in Immunology, 2022 - frontiersin.org
Fish skin is a vital immune organ that forms the first protective barrier preventing entry of
external pathogens. Rainbow trout is an important aquaculture fish species that is farmed …

Inflammation triggered by the NLRP3 inflammasome is a critical driver of diabetic bladder dysfunction

FM Hughes Jr, MR Odom, A Cervantes… - Frontiers in …, 2022 - frontiersin.org
Diabetes is a rapidly expanding epidemic projected to affect as many as 1 in 3 Americans by
2050. This disease is characterized by devastating complications brought about high …

A novel scoring system for acute myeloid leukemia risk assessment based on the expression levels of six genes

X Zhao, Y Li, H Wu - International journal of molecular …, 2018 - spandidos-publications.com
Acute myeloid leukemia (AML) is the most common type of acute leukemia and is a
heterogeneous clonal disorder. At present, the pathogenesis of AML and potential methods …

The NLRP3 inflammasome inhibitor dapansutrile attenuates cyclophosphamide-induced interstitial cystitis

S Kiran, A Rakib, UP Singh - Frontiers in Immunology, 2022 - frontiersin.org
Interstitial cystitis (IC)/bladder pain syndrome (BPS), hereafter referred together as IC, is a
clinical syndrome characterized by sterile inflammation in the bladder. While the etiology …

Long noncoding RNA UCA1 promotes cell growth, migration, and invasion by targeting miR‐143‐3p in oral squamous cell carcinoma

Q Duan, M Xu, M Wu, X Zhang, M Gan… - Cancer …, 2020 - pmc.ncbi.nlm.nih.gov
Background The long noncoding RNA (lncRNA) urothelial carcinoma‐associated 1 (UCA1)
is dysregulated in many types of tumors; however, its role in oral squamous cell carcinoma …

Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on …

FM Hughes Jr, A Allkanjari, MR Odom, H Jin, JT Purves - Life sciences, 2022 - Elsevier
Aims Diabetic bladder dysfunction (DBD) is a prevalent diabetic complication thought to
progress from overactive (OAB) to underactive (UAB) bladder. Previously we found OAB at …

The emerging role of inflammasomes as central mediators in inflammatory bladder pathology

BM Inouye, FM Hughes Jr, SJ Sexton, JT Purves - Current urology, 2018 - karger.com
Irritative voiding symptoms (eg increased frequency and urgency) occur in many common
pathologic conditions such as urinary tract infections and bladder outlet obstruction, and …

Immunity to uropathogens: the emerging roles of inflammasomes

C Hamilton, L Tan, T Miethke, PK Anand - Nature Reviews Urology, 2017 - nature.com
Urinary tract infections (UTIs) cause a huge burden of morbidity worldwide with recurrent
UTIs becoming increasingly frequent owing to the emergence of antibiotic-resistant bacterial …