Intervertebral disc (IVD) degeneration is an often investigated pathophysiological condition
because of its implication in causing low back pain. As human material for such studies is …

Intervertebral disc degeneration (IDD) is one of the main causes of low back pain, which
seriously reduces the quality of life of patients and places a heavy economic burden on their …

Aims Intervertebral disc degeneration (IVDD) is thought to be the major cause of low back
pain (LBP), which is still in lack of effective etiological treatment. Oxidative stress has been …

Intervertebral disc degeneration (IDD) is a common degenerative disease of the
musculoskeletal system that develops with age. It is regarded as the main cause of chronic …

Low back pain is a vital musculoskeletal disease that impairs life quality, leads to disability
and imposes heavy economic burden on the society, while it is greatly attributed to …

Ferroptosis, a novel type of cell death mediated by the iron‐dependent lipid peroxidation,
contributes to the pathogenesis of the intervertebral disc degeneration (IDD). Increasing …

Autophagy is an evolutionarily conserved intracellular recirculation system that delivers
cytoplasmic content to lysosomes for degradation, thereby maintaining metabolism and …

Starting from the macro-category “sleep-wake disorders”, as defined in DSM-V, the
individual pathological conditions were defined, focusing on the contextual and clinical …

Melatonin is reportedly associated with intervertebral disc degeneration (IDD). Endplate
cartilage is vitally important to intervertebral discs in physiological and pathological …

Intervertebral disc degeneration (IVDD), a widely recognized cause of lower back pain, is
the leading cause of disability worldwide. A myriad of preclinical in vivo animal models of …