Chemotherapy is one of the most established and effective treatments for almost all types of
cancer. However, the elevated toxicity due to the non-tumor-associated effects, development …

Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

Epithelial to mesenchymal transition (EMT) contributes to tumor progression, cancer cell
invasion, and therapy resistance. EMT is regulated by transcription factors such as the …

Randomized Phase II Trial of MIBG Versus MIBG, Vincristine, and Irinotecan Versus MIBG
and Vorinostat for Patients With Relapsed or Refractory Neuroblastoma: A Report From …

Background Gallbladder carcinoma (GBC) is a relatively rare but highly aggressive cancer
with late clinical detection and a poor prognosis. However, the lack of models with features …

Cancer metastasis increases the complexity of the disease and escalates patient mortality.
Traditional chemotherapy has been associated with low efficacy and marked side effects …

Squamous cell carcinoma (SCC) is a treatment‐refractory tumour which arises from the
epithelium of diverse anatomical sites such as oesophagus, head and neck, lung and skin …

Radiotherapy (RT) is one of the mainstay treatments for prostate cancer (PCa), a highly
prevalent neoplasm among males worldwide. About 30% of newly diagnosed PCa patients …

Epigenetic changes play a significant role in cancer progression, maintenance and therapy
resistance. Generally, epigenetic modifications are reversible, thereby gaining attention for …

Prader–Willi syndrome (PWS) is a complex and multisystem neurobehavioral disorder. The
molecular mechanism of PWS is deficiency of paternally expressed gene gene or genes …