[HTML][HTML] Pharmaceutical cocrystals: A review of preparations, physicochemical properties and applications
M Guo, X Sun, J Chen, T Cai - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Pharmaceutical cocrystals are multicomponent systems in which at least one component is
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …
an active pharmaceutical ingredient and the others are pharmaceutically acceptable …
Solution cocrystallization: A scalable approach for cocrystal production
With an increasing interest in cocrystals due to various advantages, demand for large-scale
cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach …
cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach …
Pharmaceutical cocrystals: a perspective on development and scale-up of solution cocrystallization
A Saha, AA Ahangar, AA Dar, S Thirunahari… - Crystal Growth & …, 2023 - ACS Publications
Pharmaceutical cocrystals represent an emergent class of successful materials designed
based on crystal engineering principles, in which the limitations of the extant drugs are …
based on crystal engineering principles, in which the limitations of the extant drugs are …
Membrane-cooling coupled crystallization with zero solvent discharge for spherical HMX: Process design, growth kinetics and mechanism
T Wang, Y Wang, S Hao, S Zhang, R Gou, H Li… - Chemical Engineering …, 2023 - Elsevier
The simultaneous achievement of crystal characteristics control and environmentally benign
is challenging the formulation processing of energetic materials (EMs). Herein, a membrane …
is challenging the formulation processing of energetic materials (EMs). Herein, a membrane …
Opportunities and challenges in mechanochemical cocrystallization toward scaled-up pharmaceutical manufacturing
Recently, pharmaceutical cocrystals have gained immense interest because of their
potential to tune mechanical, pharmacokinetic, and physicochemical properties of active …
potential to tune mechanical, pharmacokinetic, and physicochemical properties of active …
Cocrystals of carbamazepine: Structure, mechanical properties, fluorescence properties, solubility, and dissolution rate
J Ouyang, L Liu, Y Li, M Chen, L Zhou, Z Liu, L Xu… - Particuology, 2024 - Elsevier
Carbamazepine (CBZ) is an anticonvulsant with very low water solubility, presenting as a
white crystalline powder with poor mechanical properties and is hard to bend. To enhance …
white crystalline powder with poor mechanical properties and is hard to bend. To enhance …
Improvement in inhibition performance of anti-corrosion coatings using polyolefin matrix embedded with modified TiO2 nanoparticles
Corrosion remains a critical issue for steel structures, leading to costly repairs and potential
failures in industrial sectors. This study presents the development and characterization of …
failures in industrial sectors. This study presents the development and characterization of …
Investigating cocrystallization of carbamazepine with structurally compatible coformers: new cocrystal and eutectic phases with enhanced dissolution
I Sathisaran, SV Dalvi - AAPS PharmSciTech, 2021 - Springer
In this work, carbamazepine (CBZ), an anticonvulsant drug was cocrystallized with several
structurally complement coformers (coformers with amide, acid and hydrazide functional …
structurally complement coformers (coformers with amide, acid and hydrazide functional …
[PDF][PDF] Systematic review: co-crystal as efforts to improve physicochemical and bioavailability properties of oral solid dosage form
I Sopyan, B Alvin, KS Insan Sunan… - Int. J. Appl …, 2021 - researchgate.net
Water solubility and low bioavailability of active pharmaceutical ingredients are some of the
main challenges in the process of developing new drugs, especially drugs in oral solid …
main challenges in the process of developing new drugs, especially drugs in oral solid …
Continuous manufacture and scale-up of theophylline-nicotinamide cocrystals
SA Ross, AP Hurt, M Antonijevic, N Bouropoulos… - Pharmaceutics, 2021 - mdpi.com
The aim of the study was the manufacturing and scale-up of theophylline-nicotinamide (THL-
NIC) pharmaceutical cocrystals processed by hot-melt extrusion (HME). The barrel …
NIC) pharmaceutical cocrystals processed by hot-melt extrusion (HME). The barrel …