Neuroimmunology is one of the fastest-growing fields in the life sciences, and for good
reason; it fills the gap between two principal systems of the organism, the nervous system …

Several studies have shown that the gut microbiota influences behavior and, in turn,
changes in the immune system associated with symptoms of depression or anxiety disorder …

Importance The neuroinflammatory hypothesis of major depressive disorder is supported by
several main findings. First, in humans and animals, activation of the immune system causes …

Background Major depressive disorder is associated with raised peripheral inflammatory
markers. Mounting evidence also suggests that inflammation is involved in suicidal …

Despite increasing evidence supporting the neuroinflammatory theory of depression, little is
known about cerebral macrophages in individuals suffering from major depression. In the …

Substantial evidence indicates an association between clinical depression and altered
immune function. Systemic administration of bacterial lipopolysaccharide (LPS) is commonly …

Astrocyte-derived extracellular vesicles (ADEs) allow the in vivo probing of the inflammatory
status of astrocytes practical. Serum sample and ADEs were used to test the inflammatory …

Rodent models are an indispensable tool for studying etiology and progress of depression.
Since interrelated systems of neurotrophic factors and cytokines comprise major regulatory …

Aims The NLRP 3 inflammasome is a cytoplasmic multiprotein complex of the innate
immune system that regulates the cleavage of interleukin‐1β and interleukin‐18 precursors …

Mood disorders, despite the widespread availability of monoamine-based antidepressant
treatments, are associated with persistently high rates of disability, together with elevated …