Computer-aided drug design (CADD) is an emerging field that has drawn a lot of interest
because of its potential to expedite and lower the cost of the drug development process …

HRAS, NRAS and KRAS, collectively referred to as oncogenic RAS, are the most frequently
mutated driver proto-oncogenes in cancer. Oncogenic RAS aberrantly rewires metabolic …

Ferroptosis is a form of regulated cell death characterized by the accumulation of lipid
hydroperoxides. There has been significant research on the pathways leading to the …

The physical properties of lipid bilayers are sensitive to the specific type and composition of
the lipids that make up the many different types of cell membranes. Studying model bilayers …

Self-emulsifying drug delivery systems (SEDDS) offer potential for overcoming the inherent
slow dissolution and poor oral absorption of hydrophobic drugs by retaining them in a …

Lipid peroxidation is a process which is key in cell signaling and disease, it is exploited in
cancer therapy in the form of photodynamic therapy. The appearance of hydrophilic moieties …

The standard model of pore formation was introduced more than fifty years ago, and it has
been since, despite some refinements, the cornerstone for interpreting experiments related …

Plasma medicine, or the biomedical application of cold atmospheric plasma (CAP), is an
expanding field within plasma research. CAP has demonstrated remarkable versatility in …

In this review, we describe how photooxidation changes membrane properties that can
ultimately lead to permanent membrane damage. Lipid photooxidation occurs in the …

Lipid rafts display a lateral heterogeneity forming membrane microdomains that hold a
fundamental role on biological membranes and are indispensable to physiological functions …