An update on animal models of intervertebral disc degeneration and low back pain: exploring the potential of artificial intelligence to improve research analysis and …

M Alini, AD Diwan, WM Erwin, CB Little, J Melrose - JOR spine, 2023 - Wiley Online Library
Animal models have been invaluable in the identification of molecular events occurring in
and contributing to intervertebral disc (IVD) degeneration and important therapeutic targets …

[HTML][HTML] Box-Behnken Design-based formulation optimization and characterization of spray dried rutin loaded nanosuspension: State of the art

O Porwal - South African Journal of Botany, 2022 - Elsevier
Plant secondary metabolites possess excellent antioxidant properties and reported as
important source of antioxidants in nutraceuticals. Rutin is one of the plant secondary …

Withametelin, a steroidal lactone, isolated from datura innoxa attenuates STZ-induced diabetic neuropathic pain in rats through inhibition of NF-kB/MAPK signaling

A Khan, B Shal, AU Khan, MW Baig, I Ul Haq… - Food and Chemical …, 2023 - Elsevier
Diabetic neuropathic pain is one of the microvascular complications of diabetes mellitus
characterized by symmetrical pain and sensory abnormalities. A steroidal lactone isolated …

The subgroup of 2′-hydroxy-flavonoids: Molecular diversity, mechanism of action, and anticancer properties

C Bailly - Bioorganic & Medicinal Chemistry, 2021 - Elsevier
Flavonoids are abundant in nature, structurally very diversified and largely investigated.
However, the subgroup of 2′-hydroxyflavonoids is much less known and not frequently …

A mechanistic insight on phytoconstituents delivering hypoglycemic activity: a comprehensive overview

SS Raghav, B Kumar, NK Sethiya, A Kaul - Future Pharmacology, 2022 - mdpi.com
Diabetes is a long-term (chronic), challenging lifestyle (metabolic) disorder in which the
body cannot regulate the amount of sugar in the blood and majorly affecting endocrine …

Association of Dietary Flavonoids Intake With All‐Cause and Cardiovascular Disease Mortality in Diabetic Kidney Disease: A Cohort Study From the NHANES …

Q Wang, W Deng, J Yang, Y Li, H Huang… - Journal of Diabetes …, 2024 - Wiley Online Library
The relationship between dietary flavonoid intake and mortality in the diabetic kidney
disease (DKD) population is unknown. So this study is aimed at investigating the association …

Unraveling the therapeutic potential of Astilbe rivularis Buch.-Ham. ex D. Don in attenuation of diabetic neuropathy in laboratory rats

T Gupta, K Lal, R Singh - Journal of Ethnopharmacology, 2025 - Elsevier
Abstract Ethnopharmacological relevance Astilbe rivularis Buch.-Ham. ex D. Don is a rare
medicinal plant, traditionally employed for treating several disorders. The juice, decoction or …

Impact of Augmented Reality on learning Fused Deposition Modeling based 3D printing Augmented Reality for skill development

M Bakkiyaraj, G Kavitha, GS Krishnan… - Materials Today …, 2021 - Elsevier
The aim of this study is to evaluate the impact of various modes of Augmented Reality (AR)
in learning the skills associated with a 3D printing technology called Fused Deposition …

Investigation of the Hydrogen Sulfide Signaling Pathway in Schwann Cells during Peripheral Nerve Degeneration: Multi-Omics Approaches

YL Chun, WJ Eom, JH Lee, TNC Nguyen, KH Park… - Antioxidants, 2022 - mdpi.com
N-ethylmaleimide (NEM) inhibits peripheral nerve degeneration (PND) by targeting
Schwann cells in a hydrogen sulfide (H2S)-pathway-dependent manner, but the underlying …

Biomarkers and signaling pathways of diabetic nephropathy and peripheral neuropathy: Possible therapeutic intervention of rutin and quercetin

TF Roohi, S Mehdi, S Aarfi, KL Krishna, S Pathak… - Diabetology …, 2024 - Springer
Diabetic nephropathy and peripheral neuropathy are the two main complications of chronic
diabetes that contribute to high morbidity and mortality. These conditions are characterized …