Adipogenesis and metabolic health
AL Ghaben, PE Scherer - Nature reviews Molecular cell biology, 2019 - nature.com
Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …
Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products
Obesity is recognized as a severe threat to overall human health and is associated with type
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …
Emerging mechanistic understanding of cilia function in cellular signalling
Primary cilia are solitary, immotile sensory organelles present on most cells in the body that
participate broadly in human health, physiology and disease. Cilia generate a unique …
participate broadly in human health, physiology and disease. Cilia generate a unique …
Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules
D Moseti, A Regassa, WK Kim - International journal of molecular …, 2016 - mdpi.com
Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …
Adipogenesis: a complex interplay of multiple molecular determinants and pathways
The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …
The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review
Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …
Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis
Type 2 diabetes mellitus (T2DM) associated non-alcoholic fatty liver disease (NAFLD) is the
fourth-leading cause of death. Hyperglycemia induces various complications, including …
fourth-leading cause of death. Hyperglycemia induces various complications, including …
Review of signaling pathways governing MSC osteogenic and adipogenic differentiation
AW James - Scientifica, 2013 - Wiley Online Library
Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …
Molecular mechanisms of adipogenesis: the anti-adipogenic role of AMP-activated protein kinase
Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …
Adipocyte differentiation from the inside out
ED Rosen, OA MacDougald - Nature reviews Molecular cell biology, 2006 - nature.com
Improved knowledge of all aspects of adipose biology will be required to counter the
burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the …
burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the …