Alzheimer's disease is a chronic and progressive brain neurodegenerative disease affecting
over 30 million people globally. Currently, no effective treatment is available due to multiple …

Alzheimer's disease is increasingly recognized to be linked to the function and status of
metal ions, and recently, the amyloid hypothesis has been strongly intertwined with the …

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that effects 50 million
people worldwide. In this review, AD pathology and the development of novel therapeutic …

The multitarget-directed strategy offers an effective and promising paradigm to treat the
complex neurodegenerative disorder, such as Alzheimer's disease (AD). Herein, a series of …

Three new alkaloids, bersavine (3), muraricine (4), and berbostrejdine (8), together with
seven known isoquinoline alkaloids (1–2, 5–7, 9, and 10) were isolated from an alkaloidal …

Twenty known Amaryllidaceae alkaloids of various structural types, and one undescribed
alkaloid of narcikachnine-type, named narcieliine (3), have been isolated from fresh bulbs of …

A new series of multifunctional hybrids, based on the structure of the donepezil (DNP) drug,
have been developed and evaluated as potential anti Alzheimer's disease (AD) agents. The …

Alzheimer's disease (AD) is a neurodegenerative disorder mostly influencing the elderly,
and causes death due to dementia. The main pathogenic feature connected with the …

Despite tremendous research efforts at every level, globally, there is still a lack of effective
drugs for the treatment of Alzheimer′ s disease (AD). The biochemical mechanisms of this …

On the basis of our previous work, a novel series of (4-(1, 2, 4-oxadiazol-5-yl) phenyl)-2-
aminoacetamide derivatives were synthesized and evaluated as multifunctional ligands for …