Application of modified Michaelis–Menten equations for determination of enzyme inducing and inhibiting drugs

SA Saganuwan - BMC Pharmacology and Toxicology, 2021 - Springer
Background Pharmacokinetics (PK) is the process of absorption, distribution, metabolism
and elimination (ADME) of drugs. Some drugs undergo zero-order kinetics (ethyl alcohol) …

Modelling of urea hydrolysis kinetics using genetic algorithm coupled artificial neural networks in urease immobilized magnetite nanoparticles

CG Malar, M Seenuvasan, M Murugesan, SBR Carter… - Chemosphere, 2022 - Elsevier
The presence of urea in runoff from fertilized soil could be contributing to the growth of
dangerous blooms. Enzymatic urea hydrolysis is a well-known outstanding process that …

In vitro biomedical corrosion and enzyme activity inhibition on modified Cu-Zn-Al bioalloy

S Herenda, V Asanović, E Hasković, D Radonjić… - Corrosion …, 2023 - degruyter.com
The amperometric biosensor was created using a flat sheet of the Cu-Zn-Al shape memory
alloy, with a shiny surface and uniform thickness below 1 mm. The high biocompatibility and …

Halogenated boroxine increases propensity to apoptosis in leukemia (UT‐7) but not non‐tumor cells in vitro

M Hadzic, Y Sun, N Tomic, E Tsirvouli… - FEBS Open …, 2023 - Wiley Online Library
A hallmark of the development of solid and hematological malignancies is the dysregulation
of apoptosis, which leads to an imbalance between cell proliferation, cell survival and death …

Novel boron‐containing compound, halogenated boroxine, induces selective cytotoxicity through apoptosis triggering in UT‐7 leukemia

M Hadzic, L Pojskic, N Lojo‐Kadric… - … of Biochemical and …, 2022 - Wiley Online Library
Apoptosis induction is a promising approach in targeting tumor cells. As halogenated
boroxine (HB) shows antitumor activity, but its mechanism of action in hematological tumors …

Kinetics of Mediated Bioelectrocatalytic Oxidation of Glucose by Protein Extracts of Escherichia coli

MV Dmitrieva, IN Shishov, SV Shmalii… - Russian Journal of …, 2020 - Springer
The kinetics of bioelectrocatalytic oxidation of glucose by protein extracts—supersonic-
destruction products of Escherichia coli BB cells—is studied in the presence of [Fe (CN) 6] 3 …

Biochemical and histomorphological findings in Swiss Wistar rats treated with potential boron-containing therapeutic-K2 [B3O3F4OH]

A Haverić, A Durmić-Pašić, A Alić, I Mujezinović… - Journal of Trace …, 2020 - Elsevier
Background Boron and boron containing compounds are known for their biological and
protective roles being non-toxic and non-mutagenic in low concentrations. Male rats were …

Moderate Toxicity of Potential Boron-containing Therapeutic, Dipotassium-trioxohydroxytetrafl uorotriborate -K2(B3O3F4OH) in Rats and Mice

A Haveric, S Haveric, M Hadzic, J Ezic… - Brazilian Journal of …, 2023 - SciELO Brasil
Biological activity of boron-containing compounds (BCCs) has been well-known. Growing
interest and numerous applications for BCCs have been reported. Boron and boron …

Halogenated Boroxine K2[B3O3F4OH] Modulates Metabolic Phenotype and Autophagy in Human Bladder Carcinoma 5637 Cell Line

N Elez-Burnjaković, L Pojskić, A Haverić, N Lojo-Kadrić… - Molecules, 2024 - mdpi.com
Halogenated boroxine K2 [B3O3F4OH](HB), an inorganic derivative of cyclic anhydride of
boronic acid, is patented as a boron-containing compound with potential for the treatment of …

New in vitro findings about halogenated boroxine cytotoxicity and deregulation of cell death-related genes in GR-M melanoma cells

N Elez-Burnjaković, L Pojskić, A Haverić… - Arhiv za higijenu rada i …, 2023 - hrcak.srce.hr
Sažetak Anti-proliferative effects of halogenated boroxine–K2 (B3O3F4OH)(HB)–have been
confirmed in multiple cancer cell lines, including melanoma, but the exact mechanism of …