A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

One of the most important parameters in pharmacy is drug solubility. Solubility affects the
efficacy of a drug. Drug solubility has an important role in determining the concentration of a …

Lycopene is a promising biological functional component with various biological activities
and excellent pharmacological activities. However, its low water solubility and stability lead …

Solubility limited bioavailability is one of the crucial parameters that affect the formulation
development of the new chemical entities. Thus the major constraint in the pharmaceutical …

Dihydromyricetin (DHM) is an important natural flavonoid that has attracted much attention
because of its various functions such as protecting the cardiovascular system and liver …

Azithromycin (AZI) is one of the most commonly used macrolide antibiotics in children, but
has the disadvantages of a heavy bitter taste and poor solubility. In order to solve these …

Oral administration of drugs is preferred over other routes for several reasons: it is non-
invasive, easy to administer, and easy to store. However, drug formulation for oral …

This research aimed at developing ODFs containing an antipsychotic drug–aripiprazole
(ARP). ARP, as a BCS II class molecule, requires enhancing its water solubility prior to …

This study aimed to develop a solid dispersion formulation of silymarin (Silymarin-SD) using
freeze-drying method to enhance its oral bioavailability (BA) by inhibiting the intestinal first …

The advances in the development of drugs and vaccines for major infectious diseases of
tuberculosis (TB), malaria and HIV represent some of the most significant milestones in their …